Our Sponsors/Contract Research Organizations.

Representative sponsoring organizations include the following pharmaceutical and biotechnology companies:

Representative Contract Research Organizations include the following:

Our Therapeutic Expertise:

Over 25 years ago, in an effort to provide extraordinary opportunities for pharmaceutical companies to tap into the unparalleled patient population of Orange County, California, Dennis S. Riff, MD, FACG began his vision of success in clinical trials. Michael Demicco, MD and Steven Duckor, MD joined the team shortly thereafter. Within the past 25+ years, Dr. Riff and his research staff have successfully completed over 1,000 studies for an array of pharmaceutical companies.

Affiliated Medical Facilities:

• Anaheim Memorial Medical Center
• Anaheim Outpatient Surgicenter
• Chapman Medical Center
• Irvine Medical Center
• Placentia-Linda Hospital
• St. Jude Hospital
• Tustin Medical Center
• Western Medical Center - Anaheim
• Western Medical Center - Santa Ana

Advanced Clinical Research Institute also enjoys an exclusive referral agreement with a leading managed care network, providing access to over 300,000 potential participants across a full spectrum of patient populations. In addition to the network, our team recruits from within a private practice database exceeding 75,000 patients. Our independence, experienced professional management team, and the physicians' absolute commitment to "achieving success on time, within budget, accurately, and with the utmost concern for the safety of all participants" remains a benchmark upon which other trial sites measure themselves.

Other highlights of our sites include:

• A huge primary database drawn internally from our private practice.
• 48 hour turn around on all regulatory documents, budgets, research agreements, and other contracts.
• Study approval usually within one week (depending on which Central IRB is selected).
• 29 associated physicians who refer eligible patients for our studies.
• A staff of 32 full time clinical research coordinators, 3 regulatory specialists, one lab director, 5 patient recruitment personnel, a full time Data Entry department, a full time Quality Assurance department, and one registered dietician who have proven their ability to rapidly enroll large numbers of study subjects.
• A total commitment to quality research that ensures providing adequate staff up to seven days a week, if necessary.
• A proven track record of being one of the highest enrolling sites in the country in most of the studies we have performed.
• A history of quality work, including four FDA audits in the past three years for high enrollment, resulting in no findings of deficiencies and no Form 483's being issued.

Cardiology/Vascular Diseases
Gastroenterology
Musculoskeletal
Pulmonary/Respiratory Diseases