We have conducted approximately 600 clinical studies, both early-phase and late-phase, researching medications and medical devices since 1995 in a variety of therapeutic areas including:

• Arthritis
• Cardiovascular Disease
• Diabetes/Metabolic Syndrome
• Diabetic Nephropathy
• Diabetic Neuropathy
• Dyslipidemia
• Fibromyalgia
• Hypertension
• Irritable Bowel Syndrome
• Men's Health-including erectile dysfunction and overactive bladder
• Migraines/headaches
• Multiple Sclerosis
• Obesity
• Osteoporosis
• Pain
• Parkinson's Disease
• Renal Insuffiency/Proteinuria
• Women's Health-including HRT, hot flushes, over-active bladder, female sexual dysfunction

We have provided quality clinical trail services for the many pharmaceutical, biotechnology and clinical research organizations including:

Abbott, ActivX, Allergan, Amgen, Amylin, AstraZeneca, Bayer, BioSante, Boehringer Ingelheim, Bristo-Myers Squibb, Daiichi Sankyo, Diasome, Elan, Eli Lilly, Essentialis, Forest, Genentech, Generex, GlaxoSmithKline, Hoffman LaRoche, JAZZ, Johnson & Johnson, KineMed, Merck, Metabasis, Novartis, Novo Nordisk, Obecure, Parke-Davis, Pfizer, Pharmacia, Pharmacopeia, Proctor & Gamble, Purdue, Quigley, Radius, Roche, Sangamo, Sanofi-Aventis, Schering- Plough, Schwarz Biosciences, Sciele, Solvay, Takeda, TAP, Teikoku, TolerRx, Transition Therapeutics, Vivus, Wyeth, Constella, ICON Clinical Research, INC Research,Clinimetrics, Ingenix, Integrium, Kendle, MDS Pharma Services, Medpace, Omnicare, Parexel, PharmaNew, Phoenix, PPD, Inc., PRA International, Premier Research, Quintiles, Inc., ReSearch Pharmaceutical Services, Inc., SCIREX, Synergy, Synteract, and TKL Research.

We offer customer- focused, quality-based clinical research support:

• Experienced research physicians with a combined 70 years (+) of clinical research experience
• Experienced internal QA/QC monitoring with a combined 15 years monitoring experience
• Experienced research coordinators with a combined 60__ years clinical research experience
• Early-phase and late-phase capabilities
• Secure drug/data storage
• Each study is conducted in accordance with ICH-GCP and FDA standards
• High-speed internet access for staff and monitors

In addition to our staff and resources within Diablo Clinical Research, we also have long-standing relationships with and access to mammography, X-ray, MRI and medical laboratories within ½ mile radius of Diablo Clinical Research. We also employ the services of sub-investigators in various specialties including OBGyns, dermatologists, gastroenterologists, rheumatologists, opthamologists, psychiatrists, neurologists and nephrologists.

Potential sponsors of biotechnology, pharmaceutical and medical device companies are invited to visit our website at www.diabloclinical.com or contact us at studies@diabloclinical.com for more information.

Diablo Clinical Research has five clinical investigators:

Richard L. Weinstein, MD
Dr. Richard Weinstein, founder and co-medical director, built the research clinic from his private endocrinology practice of over 30 years.

Dr. Weinstein is board certified in endocrinology and internal medicine and has been involved in clinical research since 1995. He now serves as principal investigator in multiple therapeutic areas for both drug and device studies including type 1 and type 2 diabetes, diabetic neuropathy, dyslipidemia, obesity, metabolic syndrome, osteoporosis, osteoarthritis, fibromyalgia and more.

A leading expert in endocrinology, he has lectured in the areas of diabetes and osteoporosis at local, national and international meetings. Dr. Weinstein also has multiple publications in leading medical journals including Diabetes Care, Clinical Therapeutics, JAMA and the New England Journal of Medicine.

Leonard Chuck, PhD, MD
Dr. Chuck has been with Diablo Clinical Research since 2006 as a sub-investigator and in 2007 he became co-medical director of the facility and principal investigator for a variety of studies.

Prior to joining Diablo Clinical Research, Dr. Chuck was in community practice for twenty years as an internist. Prior to his community work, Dr. Chuck spent ten years as a clinical/laboratory researcher at several major academic institutions including UCLA, Cedars of Lebanon, The Cardiovascular Research Institute at UCSF, The University of Antwerp in Belgium and The University of Calgary.

Mark Christiansen, MD
Dr. Christiansen has been a sub-investigator / principal investigator and early-phase unit medical director with Diablo Clinical Research since 2007. He is an expert and specializes in glucose clamp studies. Dr. Christiansen has prior clinical research experience in over eighty studies including (but not limited to) diabetes type 1 and type 2, neuropathy, dyslipidemia, hypertension, metabolic syndrome, fibromyalgia, osteoporosis, osteoarthritis and obesity.

Dr. Christiansen's certifications include the National Board of Medical Examiners, the American Board of Internal Medicine, the American Board of Diabetes, Endocrinology and Metabolism and he is a certified clinical densitometrist.

Lambert Chee, MD
Dr. Chee, a sub-investigator and principal investigator, has been with Diablo Clinical Research since 2000. Dr. Chee is also currently the Medical Director at the Cardia Heart Recirculation Center in Walnut Creek, CA.

Dr. Chee's certifications include the National Board of Medical Examiners, the American Board of Internal Medicine and the Subspecialty Board of Cardiovascular Disease.

Helen Stacey, MD
Dr. Stacey, a sub-investigator with Diablo Clinical Research since 2000, is an internist with a Masters in Public Health. Dr. Stacey has prior clinical research experience conducting studies of potential HIV vaccines at the University of Washington AIDS Vaccine Unit.

Dr. Stacey holds certifications from the National Board of Medical Examiners and the American Board of Internal Medicine.

Michael R. Stein, M.D
Dr. Michael Stein joined Diablo Clinical Research as a principal investigator in 2008. Dr. Stein is an expert and specializes in migraines, Parkinson's Disease and Multiple Sclerosis studies. Dr. Stein has prior clinical research experience in over fifty studies at the Neurological Research Institute of the East Bay since 2001.

Dr. Stein's certifications include the American Board of Psychiatry and Neurology and the National Board of Medical Examiners.

The staff at Diablo Clinical Research represents our core values which include excellent patient care, valuable study data and community health education.

• Emily Galdes, VP and COO of Diablo Clinical Research, has over 6 years of clinical trial administration experience.
• Lori Vitti, Director of Finance & Administration, has over 20 years finance and administration experience.
• Charlette Vargas, Director of Regulatory Compliance, has over thirteen years of research regulatory experience.
• Catherine Morimoto, Director of Clinical Operations, has over 6 years of clinical research experience.

Support Staff for both early and late-phase units:

• Five physicians/clinical investigators
• One laboratory technician
• Three in-house regulatory personnel
• Two in-house QA/QC personnel
• Five recruitment specialists
• One registered dietitian
• Three CDPH-certified DXA technicians
• Three CDPH-certified PFT technicians

Early Phase Dedicated Staff:

• One senior coordinator
• Two research nurses
• One research associate
• One administrative assistant
• Ten RNs on-call 24/7

Diablo Clinical Research is located in the San Francisco bay area which is home to over 5.4 million people in a six county recruitment region. The San Francisco population is ethnically diverse with approximately 21% Asians, 20% Hispanics and 8% African-Americans.

Cardiology/Vascular Diseases
Endocrinology
Gastroenterology
Musculoskeletal
Nephrology/Urology
Neurology
Obstetrics/Gynecology
Rheumatology