Clinical Research Facility
Boston, Massachusetts
We've found
157 trials
at this facility
Multiple Myeloma Clinical Trial
Updated: 5/11/2017
A Study of Pembrolizumab (MK-3475) in Combination With Standard of Care Treatments in Participants With Multiple Myeloma (MK-3475-023/KEYNOTE-023)
Status: Enrolling,
Phase
I
Updated: 5/11/2017
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Adv Solid Malig - H&N SCC, ATM Pro / Def NSCLC, Gastric & Breast Cancer Clinical Trial
Updated: 12/31/1969
Ascending Doses of AZD6738 in Combination With Chemotherapy and/or Novel Anti Cancer Agents
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Breast Cancer Clinical Trial
Updated: 12/31/1969
Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Differentiated Thyroid Cancer Clinical Trial
Updated: 3/15/2016
An Expanded Access Program With Lenvatinib for the Treatment of Radioiodine-Refractory Differentiated Thyroid Cancer
Status: Enrolling
Updated: 3/15/2016
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Contraception Clinical Trial
Updated: 4/13/2016
Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring in Women at Risk for Pregnancy (MK-8342B-061)
Status: Enrolling,
Phase
III
Updated: 4/13/2016
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Oncology Clinical Trial
Updated: 12/31/1969
A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Urothelial Cancer Clinical Trial
Updated: 5/17/2016
Study of Pembrolizumab (MK-3475) in Participants With Advanced Urothelial Cancer (MK-3475-052/KEYNOTE-52)
Status: Enrolling,
Phase
II
Updated: 5/17/2016
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Nephrology / Urology Clinical Trial
Updated: 12/31/1969
Dose Escalation, Expansion Study of Vofatamab (B-701) in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Multiple Myeloma Clinical Trial
Updated: 5/31/2017
Study of Lenalidomide and Dexamethasone With or Without Pembrolizumab (MK-3475) in Participants With Newly Diagnosed Treatment Naive Multiple Myeloma (MK-3475-185/KEYNOTE-185)
Status: Enrolling,
Phase
III
Updated: 5/31/2017
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Oncology Clinical Trial
Updated: 12/31/1969
A Phase I/II Study of MEDI4736 in Combination With Olaparib in Patients With Advanced Solid Tumors.
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Nasopharyngeal Neoplasms Clinical Trial
Updated: 12/31/1969
Study of Pembrolizumab (MK-3475) in Platinum Pre-treated Recurrent/Metastatic Nasopharyngeal Cancer (MK-3475-122/KEYNOTE-122)
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Cystic Fibrosis Clinical Trial
Updated: 12/31/1969
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Ivacaftor in Subjects With Cystic Fibrosis Who Are Less Than 24 Months of Age and Have a CFTR Gating Mutation
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Advanced or Metastatic Solid Tumors Clinical Trial
Updated: 12/31/1969
A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-042, an Anti-PD-1 Monoclonal Antibody, in Patients With Advanced Solid Tumors
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Colorectal Carcinoma Clinical Trial
Updated: 1/11/2018
Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177)
Status: Enrolling,
Phase
III
Updated: 1/11/2018
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Bladder Cancer Clinical Trial
Updated: 12/31/1969
Study of Pembrolizumab (MK-3475) in Participants With High Risk Non-muscle Invasive Bladder Cancer (MK-3475-057/KEYNOTE-057)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Pulmonary Arterial Hypertension Clinical Trial
Updated: 12/31/1969
Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy
Status: Enrolling,
Phase
IV
Updated: 12/31/1969
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MPN (Myeloproliferative Neoplasms) Clinical Trial
Updated: 12/31/1969
Myelofibrosis and Essential Thrombocythemia Observational Study (MOST)
Status: Enrolling,
Phase
Updated: 12/31/1969
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Bradycardia Clinical Trial
Updated: 12/31/1969
Micra Transcatheter Pacing System Post-Approval Registry
Status: Enrolling,
Phase
Updated: 12/31/1969
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Breast Cancer Clinical Trial
Updated: 12/31/1969
Phase 1 / 2 Study of SAR439859 Single Agent and in Combination With Palbociclib in Postmenopausal Women With Estrogen Receptor Positive Advanced Breast Cancer
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Non-Small Cell Lung Cancer Clinical Trial
Updated: 12/31/1969
Phase II Umbrella Study of Novel Anti-cancer Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy.
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Myopia Clinical Trial
Updated: 12/31/1969
CHAMP: Study of NVK-002 in Children With Myopia
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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AIS Clinical Trial
Updated: 12/31/1969
NBP in Adult Patients With Acute Ischemic Stroke (AIS)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Alzheimer's Disease Clinical Trial
Updated: 12/31/1969
Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Heart Failure Clinical Trial
Updated: 12/31/1969
Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart Failure
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Asthma Clinical Trial
Updated: 12/31/1969
Study to Evaluate Efficacy and Safety of Benralizumab in Reducing Oral Corticosteroid Use in Adult Patients With Severe Asthma
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Heart Failure With Preserved Ejection Fraction Clinical Trial
Updated: 12/31/1969
Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure.
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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HIV INfections Clinical Trial
Updated: 11/29/2016
Tipranavir in Patients With Progressive, Systemic HIV-1 Disease Who Have Failed or Are Intolerant to Currently Approved Treatments for HIV Infection
Status: Enrolling
Updated: 11/29/2016
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Cardiology / Vascular Diseases, Otolaryngology Clinical Trial
Updated: 12/31/1969
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
Status: Enrolling,
Phase
Updated: 12/31/1969
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Cancer, Solid Tumor Clinical Trial
Updated: 4/30/2014
Study of MK-3475 in Participants With Progressive Locally Advanced or Metastatic Carcinoma, Melanoma, or Non-small Cell Lung Carcinoma (P07990/MK-3475-001/KEYNOTE-001)
Status: Enrolling,
Phase
I
Updated: 4/30/2014
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Immunology / Infectious Diseases Clinical Trial
Updated: 8/16/2012
Study to Investigate the Efficacy and Safety of GS-7977 Plus Ribavirin for 12 Weeks in Chronic Genotype 2 and 3 Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) Co-Infected Subjects
Status: Enrolling
Updated: 8/16/2012
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Plaque Psoriasis Clinical Trial
Updated: 4/24/2014
A Study to Evaluate the Efficacy and Safety/Tolerability of Subcutaneous SCH 900222/MK-3222 in Participants With Moderate-to-Severe Chronic Plaque Psoriasis (P07771/MK-3222-011)
Status: Enrolling,
Phase
III
Updated: 4/24/2014
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Head and Neck Squamous Cell Carcinoma HNSCC Clinical Trial
Updated: 9/23/2015
Study of MK-3475 (Pembrolizumab) in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma After Treatment With Platinum-based and Cetuximab Therapy (MK-3475-055/KEYNOTE-055)
Status: Enrolling,
Phase
II
Updated: 9/23/2015
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Urothelial Cancer Clinical Trial
Updated: 9/23/2015
A Study of Pembrolizumab (MK-3475) Versus Paclitaxel, Docetaxel, or Vinflunine for Participants With Advanced Urothelial Cancer (MK-3475-045/KEYNOTE-045)
Status: Enrolling,
Phase
III
Updated: 9/23/2015
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Neovascular Age-Related Macular Degeneration Clinical Trial
Updated: 2/26/2016
Study of Intravitreal REGN2176-3 in Patients With Neovascular ("Wet") Age-Related Macular Degeneration (AMD)
Status: Enrolling,
Phase
II
Updated: 2/26/2016
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Heart Failure Clinical Trial
Updated: 12/31/1969
Sentus QP - Extended CRT Evaluation With Quadripolar Left Ventricular Leads
Status: Enrolling
Updated: 12/31/1969
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Acute Bacterial Skin and Skin Structure Infections Clinical Trial
Updated: 6/13/2016
Oral Sodium Fusidate (CEM-102) Versus Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections
Status: Enrolling,
Phase
III
Updated: 6/13/2016
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Immunology / Infectious Diseases Clinical Trial
Updated: 4/13/2016
Pharmacokinetic and Safety Study of Ceftolozane/Tazobactam in Pediatric Participants Receiving Antibiotic Therapy for Proven or Suspected Gram-negative Infection or for Peri-operative Prophylaxis (MK-7625A-010)
Status: Enrolling,
Phase
I
Updated: 4/13/2016
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Bacterial Pneumonia Clinical Trial
Updated: 12/31/1969
Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014)
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 9/11/2017
Study of Pembrolizumab (MK-3475) in Participants With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma or Relapsed or Refractory Richter Syndrome (MK-3475-170/KEYNOTE-170)
Status: Enrolling,
Phase
II
Updated: 9/11/2017
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Ovarian Neoplasms Clinical Trial
Updated: 6/28/2016
Efficacy and Safety Study of Pembrolizumab (MK-3475) in Women With Advanced Recurrent Ovarian Cancer (MK-3475-100/KEYNOTE-100)
Status: Enrolling,
Phase
II
Updated: 6/28/2016
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Dysmenorrhea Clinical Trial
Updated: 7/27/2016
Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring in Treatment of Women With Primary Dysmenorrhea (MK-8342B-060)
Status: Enrolling,
Phase
III
Updated: 7/27/2016
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Hepatocellular Carcinoma Clinical Trial
Updated: 10/27/2017
Study of Pembrolizumab (MK-3475) vs. Best Supportive Care in Participants With Previously Systemically Treated Advanced Hepatocellular Carcinoma (MK-3475-240/KEYNOTE-240)
Status: Enrolling,
Phase
III
Updated: 10/27/2017
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Rheumatology, Orthopedics / Podiatry Clinical Trial
Updated: 12/31/1969
Actis Total Hip System 2 Year Follow-up
Status: Enrolling
Updated: 12/31/1969
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Advanced or Metastatic Solid Tumors Clinical Trial
Updated: 12/31/1969
A Phase 1 Study of TSR-022, an Anti-TIM-3 Monoclonal Antibody, in Patients With Advanced Solid Tumors (AMBER)
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Glycogen Storage Disease Type II-Pompe's Disease Clinical Trial
Updated: 12/31/1969
Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies neoGAA and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Malignant Solid Tumor Clinical Trial
Updated: 12/31/1969
A First-in-human Study of the Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of SAR439459 Monotherapy and Combination of SAR439459 and REGN2810 in Patients With Advanced Solid Tumors
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Prostate Cancer Clinical Trial
Updated: 8/30/2017
Validation of Software-based Fusion of Ultrasound and MRI Images of the Prostate
Status: Enrolling
Updated: 8/30/2017
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Epilepsy, Focal Seizures, Partial Seizures Clinical Trial
Updated: 12/31/1969
Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Cardiac Rhythm Disorder Clinical Trial
Updated: 5/2/2018
3T MRI CIED Post-Approval Study
Status: Enrolling,
Phase
Updated: 5/2/2018
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Relapsing-Remitting Multiple Sclerosis Clinical Trial
Updated: 12/31/1969
Phase 3 Efficacy and Safety Study of BG00012 in Pediatric Subjects With Relapsing-remitting Multiple Sclerosis (RRMS)
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Immunology / Infectious Diseases, Neurology, Pulmonary / Respiratory Diseases Clinical Trial
Updated: 12/31/1969
Study to Evaluate Tezepelumab on Airway Inflammation in Adults With Uncontrolled Asthma (CASCADE)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Neoplasm Clinical Trial
Updated: 12/31/1969
Safety, Preliminary Efficacy and PK of Isatuximab (SAR650984) Alone or in Combination With Atezolizumab in Patients With Advanced Malignancies
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Heart Failure Clinical Trial
Updated: 12/31/1969
Safety and Tolerability Study of AZD4831 in Patients With Heart Failure.
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Durvalumab and Tremelimumab for Pediatric Malignancies
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Carcinoma, Non-Small-Cell Lung Clinical Trial
Updated: 12/31/1969
Durvalumab vs Placebo Following Stereotactic Body Radiation Therapy in Early Stage Non-small Cell Lung Cancer Patients
Status: Upcoming,
Phase
III
Updated: 12/31/1969
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