Clinical Trials in Massachusetts

Are you looking to enroll in a clinical trial in Massachusetts? With new trials like "Study of Atezolizumab + Bevacizumab in Patients With Advanced Non-Clear Cell Renal Cell Carcinoma" and "A Safety and Efficacy Study of Oral AG-120 Plus Subcutaneous Azacitidine and Oral AG-221 Plus Subcutaneous Azacitidine in Subjects With Newly Diagnosed Acute Myeloid Leukemia (AML)", the Bay State has established itself as a great location for clinical research studies, particularly in cities like Boston and Worcester.

While some individuals are looking for paid clinical trials, others want to help advance neurology and pharmacology clinical research in Massachusetts. To begin your search for Massachusetts clinical trials, use the form on the right.

Use our guide to learn which trials are right for you!


We've found
5,403
clinical trials in
Massachusetts

Hematology Clinical Trial
A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients Without Inhibitors
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Alcohol Dependence Clinical Trial
Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism
Status: Enrolling, Phase III
Updated: 1/16/2018
mi
from
Boston, MA
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Psychiatry / Psychology Clinical Trial
Motivation and Skills Support (MASS)
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Tattoo Removal Clinical Trial
Multi-Wavelength Laser Tattoo Removal Pivotal Study
Status: Enrolling
Updated: 1/18/2018
mi
from
Chestnut Hill, MA
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Immunology / Infectious Diseases, Musculoskeletal, Oncology Clinical Trial
Augmented Reality Headset as Adjunct Display Monitor in AMIGO
Status: Enrolling
Updated: 1/18/2018
mi
from
Boston, MA
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Oncology, Other Clinical Trial
Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing
Status: Enrolling
Updated: 1/19/2018
mi
from
Boston, MA
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Advanced Melanoma Clinical Trial
Immunologic Determinants of Response to Pembrolizumab (MK-3475) in Advanced Melanoma (MK-3475-161/KEYNOTE-161)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Peanut Allergy Clinical Trial
Evaluating the Safety and Efficacy of Fecal Microbiota Transplant in Peanut Allergic Patients
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Boston, MA
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Breast Cancer Clinical Trial
Supine MRI in Breast Cancer Patients Receiving Neoadjuvant Therapy
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Environmental Exposure to Ultraviolet Light Clinical Trial
HealthSmart: Promoting Healthy Lifestyles for Young Adult Cancer Survivors Using Educational Videos
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Cardiology / Vascular Diseases, Hematology, Immunology / Infectious Diseases, Nephrology / Urology Clinical Trial
Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Ulcerative Colitis Clinical Trial
An Induction Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 1)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Burlington, MA
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Cardiology / Vascular Diseases Clinical Trial
International BPA Registry
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Pulmonary Hypertension Clinical Trial
Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Pulmonary Hypertension Clinical Trial
Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of Vortioxetine
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Boston, MA
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Psychiatry / Psychology Clinical Trial
Brexpiprazole Study
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Boston, MA
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Cardiology / Vascular Diseases, Dermatology / Plastic Surgery Clinical Trial
Long-Term Study of EN3835 in Edematous Fibrosclerotic Panniculopathy (Cellulite)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Quincy, MA
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Prader-Willi Syndrome Clinical Trial
A Study of Diazoxide Choline in Patients With Prader-Willi Syndrome
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Psychiatry / Psychology Clinical Trial
Cognitive Control Training for Urgency in a Naturalistic Clinical Setting
Status: Enrolling
Updated: 12/31/1969
mi
from
Belmont, MA
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Metastatic Endometrial Cancer Clinical Trial
Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer and of Avelumab/Talazoparib in Patients With MSS Recurrent or Persistent Endometrial Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Ankylosing Spondylitis Clinical Trial
Effect of Secukinumab on Radiographic Progression in Ankylosing Spondylitis as Compared to GP2017 (Adalimumab Biosimilar)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Lung Cancer Clinical Trial
Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the MEK Inhibitor Binimetinib (MEK162) for Patients With Advanced KRAS Mutant Non-Small Cell Lung Cancer
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
Boston, MA
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Cardiology / Vascular Diseases Clinical Trial
PARTNER 3 Trial - Mitral Valve in Valve
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Clinical Trial
Expanded Access Program to Provide Treatment With Pitolisant to Adult Patients in the U.S. With Excessive Daytime Sleepiness Associated With Narcolepsy With or Without Cataplexy
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Neurology, Oncology Clinical Trial
Evaluating a Clinician Support Algorithm to Enhance Implementation of Evidence-Based Chemotherapy-Induced Peripheral Neuropathy Assessment and Management Recommendations
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Atopic Dermatitis Clinical Trial
Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Primary Sclerosing Cholangitis Clinical Trial
Sulfasalazine for the Treatment of Primary Sclerosing Cholangitis
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Canavan Disease Clinical Trial
A Natural History Study of Canavan Disease
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Pancreatic Cancer Clinical Trial
Losartan and Nivolumab in Combination With FOLFIRINOX and SBRT in Localized Pancreatic Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Metastatic Castration-resistant Prostate Cancer Clinical Trial
Onvansertib in Combination With Abiraterone and Prednisone in Adult Patients With Metastatic Castration-Resistant Prostate Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Fabry Disease Clinical Trial
Extension Study of 1 mg/kg Pegunigalsidase Alfa in Patients With Fabry Disease
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Cardiology / Vascular Diseases Clinical Trial
Pecto-Intercostal Fascial Block for Postoperative Analgesia After Cardiac Surgery
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Neoplasms Clinical Trial
Long-Term Follow-up Protocol for Subjects Treated With Gene-Modified T Cells
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Boston, MA
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Depressive Disorder, Treatment-Resistant Clinical Trial
A Study to Evaluate the Efficacy, Pharmacokinetics, Safety and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Watertown, MA
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Fragile X Syndrome Clinical Trial
AFQ056 for Language Learning in Children With FXS
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Alzheimer Disease (AD) Clinical Trial
A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Hematology Clinical Trial
Extended Access of Momelotinib in Adults With Myelofibrosis
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Pre-Exposure Prophylaxis Clinical Trial
Optimizing PrEP Adherence for Young Men Who Have Sex With Men
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Focal Segmental Glomerulosclerosis Clinical Trial
Study of Sparsentan in FSGS
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Springfield, MA
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Other Clinical Trial
Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Autism Spectrum Disorder Clinical Trial
A Study of Balovaptan in Adults With Autism Spectrum Disorder With a 2-Year Open-Label Extension
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Ankylosing Spondylitis Clinical Trial
Study Estimating the Clinical Difference Between 300 mg and 150 mg of Secukinumab Following Dose Escalation to 300 mg in Patients With Ankylosing Spondylitis
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Boston, MA
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Oncology, Psychiatry / Psychology Clinical Trial
Sexual Health and Rehabilitation After Ovarian Suppression Treatment
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Ovarian Cancer Clinical Trial
Pilot Study of Rosuvastatin and Enoxaparin Thromboprophylaxis Following Ovarian Cancer Surgery (O-STAT Study)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Drug Effect Clinical Trial
Pharmacokinetics of Bivalirudin for Pediatric Anticoagulation
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Pulmonary Arterial Hypertension Clinical Trial
A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (PAH)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Chronic Lymphocytic Leukemia Clinical Trial
Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
Boston, MA
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Nephrology / Urology Clinical Trial
A Study of CCX140-B in Subjects With FSGS
Status: Enrolling, Phase II
Updated: 12/31/1969
MGH
mi
from
Boston, MA
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Amyloid Cardiomyopathy Clinical Trial
Open-Label Study of AG10 in Patients With Cardiomyopathy
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Dermatology / Plastic Surgery Clinical Trial
Targeting Surgeons' Decision-Making for Cleft Lip Surgery
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Cardiology / Vascular Diseases, Endocrinology, Ophthalmology Clinical Trial
A Study to Evaluate the Safety of THR-149 in Subjects With Diabetic Macular Edema (DME)
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Boston, MA
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Oncology, Other Clinical Trial
Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults With Relapsed ALL
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Boston, MA
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Thumb Osteoarthritis Clinical Trial
Turmeric for Patients With Basal Joint Arthritis
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Gastroesophageal Reflux Disease (GERD) Clinical Trial
A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Psychiatry / Psychology Clinical Trial
OKS for the Treatment of Hemispatial Neglect
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Breast Cancer Clinical Trial
A Study Of Pembrolizumab In Combination With Trastuzumab-DM1
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Boston, MA
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Diabetic Macular Edema Clinical Trial
A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (YOSEMITE)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Dermatology / Plastic Surgery, Immunology / Infectious Diseases, Neurology, Oncology, Reproductive Clinical Trial
Study to Investigate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years and Over With Moderate to Severe Atopic Dermatitis With the Option of Rescue Treatment in Flaring Subjects
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Bladder Cancer Clinical Trial
CV301 Combined With PD-1/L1 Blockade in Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Hidradenitis Suppurativa Clinical Trial
A Study to Evaluate the Efficacy, Safety, and Tolerability of Guselkumab for the Treatment of Participants With Moderate to Severe Hidradenitis Suppurativa (HS)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Musculoskeletal Clinical Trial
Medication Education for Dosing Safety
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Depressive Disorder, Major Clinical Trial
Study of Monotherapy Rapastinel in the Prevention of Relapse in Patients With Major Depressive Disorder (MDD)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Oral Lichen Planus Clinical Trial
Intra-oral Treatment of OLP With Rivelin®-CLO Patches
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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HIV/AIDS Clinical Trial
Adolescent Master Protocol for Participants 18 Years of Age or Older - Lite
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Rheumatology Clinical Trial
Study of Resiniferatoxin for Knee Pain in Moderate to Severe Osteoarthritis
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Boston, MA
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Oncology Clinical Trial
A Biospecimen Collection Study in BRAF-V600E Mutated Recurrent Gliomas
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Cardiology / Vascular Diseases, Hematology Clinical Trial
Efficacy and Safety of Apixaban in the Treatment of Heparin Induced Thrombocytopenia (HIT)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Hematology, Oncology, Other Clinical Trial
ABL001 + Dasatinib + Prednisone in BCR-ABL+ B-ALL or CML
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Boston, MA
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Desmoid Tumor Clinical Trial
Phase I, Open-label, Non-randomized Study to Evaluate Safety of BC2059
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Boston, MA
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Heart Failure Clinical Trial
VITROS Immunodiagnostic Products NT-proBNP II
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Pulmonary / Respiratory Diseases, Other Clinical Trial
Inpatient ICOUGH RECOVERY App Version 2.0
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Breast Cancer Clinical Trial
ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Milford, MA
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Neurology, Psychiatry / Psychology Clinical Trial
Boston Outcomes of Autism in Toddlers Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Oncology Clinical Trial
EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Depression Clinical Trial
Group Therapy for Depressed Dementia Caregivers
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Mental Fatigue Clinical Trial
A Tele-mental Health Intervention to Support Parents Caring for a Technology-dependent Child at Home
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Chronic Lymphocytic Leukemia (CLL) Clinical Trial
Acalabrutinib, Venetoclax, and Obinutuzumab for Initial Therapy of CLL
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Clinical Trial
Provider Variability in the Use of Neuromuscular Blocking Drugs and Reversal
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Wet Age-Related Macular Degeneration Clinical Trial
AAVCAGsCD59 for the Treatment of Wet AMD
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Boston, MA
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Carcinoma, Non-Small-Cell Lung Clinical Trial
Osimertinib In EGFR Mutant Lung Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Autism Spectrum Disorder Clinical Trial
Study of Neuroimaging Biomarkers of Social Cognition Deficits in Adolescents (Age 13-17) With Autism Spectrum Disorder and Effects of Gabapentin
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Worcester, MA
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Cystic Fibrosis Clinical Trial
Study Assessing PTI-428 Safety, Tolerability, Pharmacokinetics and Effect in Subjects With Cystic Fibrosis
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Aortic Valve Stenosis Clinical Trial
CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis Requiring Aortic Valve Replacement
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Idiopathic Parkinson Disease Clinical Trial
Voice Treatment for Parkinson's Disease
Status: Enrolling
Updated: 12/31/1969
mi
from
Amherst, MA
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Metastatic Melanoma Clinical Trial
A Personal Cancer Vaccine (NEO-PV-01) and APX005M or Ipilimumab With Nivolumab in Patients With Advanced Melanoma
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Boston, MA
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Focal Segmental Glomerulosclerosis Clinical Trial
A Study of CCX140-B in Subjects With Primary FSGS and Nephrotic Syndrome
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Ovarian Cancer Clinical Trial
A Phase 3 Comparison of Platinum-Based Therapy With TSR-042 and Niraparib Versus Standard of Care Platinum-Based Therapy as First-Line Treatment of Stage III or IV Nonmucinous Epithelial Ovarian Cancer
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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Alzheimer Disease Clinical Trial
Effect of Modulating Gamma Oscillations Using tACS
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Oncology Clinical Trial
COM701 in Subjects With Advanced Solid Tumors
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Boston, MA
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Uterine Cancer Clinical Trial
AZD1775 in Women With Recurrent or Persistent Uterine Serous Carcinoma
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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Depressive Disorder, Major Clinical Trial
Study of Adjunctive or Monotherapy Rapastinel Treatment in Patients With Major Depressive Disorder (MDD)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Worcester, MA
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Cardiology / Vascular Diseases, Gastroenterology, Immunology / Infectious Diseases, Other Clinical Trial
Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Primary Biliary Cholangitis Clinical Trial
ENHANCE: Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Response to or an Intolerance to Ursodeoxycholic Acid (UDCA)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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CNS Vasculitis Clinical Trial
Magnetic Resonance Imaging of Intracranial Vasculopathies
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Oncology Clinical Trial
Development of a Positive Psychology Intervention to Improve Mood and HRQoL in Patients Post-HSCT - Proof of Concept
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Major Depressive Disorder Clinical Trial
A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Methuen, MA
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HIV Clinical Trial
Effects of Biktarvy on CFR in Stable HIV Patients
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
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