Our facility specializes in pulmonary and sleep medicine related clinical research activities. We have worked with numerous major pharmaceutical companies and several CRO's performing phase II, III and IV studies. Trials have been conducted in COPD, asthma, AECB, atrial fibrillation, DVT/PE, pneumonia, obesity, and nocturnal hypoxemia. We have also performed phase IIIb studies.

Thomas M. Siler, MD is board certified in Internal Medicine, Pulmonary Diseases and Sleep Medicine. He has conducted clinical research in his practice since 1990 in both inpatient and outpatient studies. He has been principal investigator in over 70 trials. He has attended IRB sponsored GCP training. Subinvestigators include Frank Calandrino, MD, Sergio G. Garcia, M.D., Stacey Brown APRN, V. Christine Champagne APRN, CCRC, and Jill Fritz, APRN.

Mitchell Champagne, RPh, CCRC is director of research. He has conducted numerous clinical research trials since 1997.

Marcia Gaddy, RN, CCRC is a study coordinator. She has conducted clinical research since 1999.

Billie Greenwell, RN, CCRC is a study coordinator. She has conducted clinical research since 2002.

Krista Haggard, RMA CCRC has been involved in healthcare in our office since 1993 and has recently joined our research team as our newest Certified Coordinator.

Kasey Seyer, B.S., CCRC is a study coordinator. She has conducted clinical research since 2006.

Adult subjects with lung and sleep disorders are available through our private practice. We have more than 6,000 active patients in our practice. We also have access to subjects throughout the St. Louis metropolitan area with a population of over 2 million. We have arrangements for local lodging nearby for accommodating patients requiring long study visits who live outside our immediate area.

Cardiology/Vascular Diseases
Immunology/Infectious Diseases
Pulmonary/Respiratory Diseases