St. Luke's University Health Network (SLUHN) is a nonprofit, regional, fully integrated, nationally recognized Network providing care, primarily in Lehigh, Northampton, Carbon, Schuylkill, Bucks, Montgomery, Berks and Monroe counties in Pennsylvania and in Warren County, New Jersey.

St. Luke's became a multi-state provider with the February 2012 addition of St. Luke's Warren Hospital (a 214-bed acute care hospital in Phillipsburg, NJ). Other recent significant additions include:St. Luke's Wind Gap Medical Center, St. Luke's West End Medical Center and St. Luke's Pocono Outpatient Center.