Intracardiac T-wave Alternans and Ischemia



Status:Completed
Conditions:Peripheral Vascular Disease
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:Any
Updated:10/21/2012
Start Date:August 2008
End Date:May 2012
Contact:Jose' M Dizon, MD
Email:jmd11@columbia.edu
Phone:212-305-8559

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Intracardiac T-wave Alternans and Ischemia During Percutaneous Coronary Interventions


T-wave alternans is a test that looks at microvolt changes in the T-wave on a beat to beat
basis. The presence or absence of such changes has been shown to predict or exclude future
arrhythmic events. The mechanism of T-wave alternans is unclear, but may relate to calcium
metabolism in the heart, and may be affected by conditions such as ischemia or heart
failure.

The purpose of this study is to determine whether T-wave alternans, as measured through the
lead of an implantable defibrillator, is produced by acute ischemia induced by occlusion
during percutaneous coronary interventions.


Inclusion Criteria:

- patient with CAD undergoing PCI with appropriate Medtronic implantable defibrillator.

Exclusion Criteria:

- non-elective procedure

- non-qualifying defibrillator type.
We found this trial at
1
site
630 W 168th St
New York, New York
212-305-2862
Columbia University Medical Center Situated on a 20-acre campus in Northern Manhattan and accounting for...
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mi
from
New York, NY
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