Validation of Hand Held Indirect Calorimeter in Overweight and Obese Patients

1. Background and Rationale: With the growing number of overweight and obese Americans,
health professionals need accurate and convenient tools to help personalize weight loss
programs. Portable indirect calorimetry measurements are more expensive than handheld
devices and often limited to research setting only, making them impractical for
clinical use. Additionally equations used to estimate resting metabolic rate may be
significantly inaccurate in overweight patients. Several studies have been conducted to
determine the accuracy of handheld devices, however none have been done in the
overweight and obese populations. If handheld calorimeters can accurately measure
resting metabolic rate in overweight and obese patients, these tests may be used to
improve and personalize weight management programs.

2. Key Objectives: To determine in a group of overweight or obese volunteers if a handheld
indirect calorimeter can accurately measures oxygen consumption to determine resting
metabolic rate.

Inclusion Criteria:

- Age at least 18 years (no upper limit).

- Able to fast overnight.

- Have a BMI no less than 25 kg/m2.

Exclusion Criteria:

- All others