Gas Embolism With Use of Argon Plasma Coagulation



Status:Recruiting
Conditions:Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:4/2/2016
Start Date:July 2008
Contact:Adnan Majid, MD
Email:amajid@bidmc.harvard.edu
Phone:617-632-8353

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The purpose of this study is to use transesophageal echocardiography (TEE) to determine the
incidence, severity, and clinical significance of gas bubbles during argon plasma
coagulation (APC).

Gas embolism is a rare but serious complication of APC. We will use TEE to monitor for gas
bubbles during APC. APC will be terminated if gas bubbles are associated with ischemic heart
rhythms, wall motion abnormalities, or if large gas bubbles are noted in the left ventricle.

Inclusion Criteria:

- Adults (male and female) 18 years of age or older

- Clinical indication for bronchoscopy (hemoptysis, airway obstruction, tumor excision,
granulation tissue that is impairing endobronchial stent performance)

- Ability of the patient or proxy to read, comprehend, and sign informed consent
document.

Exclusion Criteria:

- Presence of esophageal disorders that may complicate transesophageal echocardiography
(strictures, varices, fistula, prior esophageal surgery)

- Presence of coagulopathy or other bleeding diathesis

- Inability to tolerate brief periods of apnea

- Presence of pulmonary vascular disease

- Pregnant women will not be included in this study because the potential fetal
hypoxemia is not an acceptable risk.

- No exclusions will be made based on gender or race.
We found this trial at
1
site
330 Brookline Ave
Boston, Massachusetts 02215
617-667-7000
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
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from
Boston, MA
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