A Prospective Study Evaluating the Performance of Nanotite Osseotite Implants When Placed by Graduate Student Programs

This multicenter, prospective, randomized-controlled study will compare the performance of
the Nanotite vs. the standard Ossotite implants when placed by graduate students with little
or no prior experience. Enrolled patients will have the study site(s) randomized to either a
Nanotite (test) or an Osseotite (control) implant. The manner of treatment observed at the
participating center will be followed for this study.

Study Hypothesis: The performance of the Nanotite implant in this study will be no different
than or superior to that of the Osseotite implant placed during the early period of graduate
student training.

Inclusion Criteria:

- patients of either sex and of any race, 18 years of age or older

- patients for whom a decision has already been made to use dental implants for treating
edentulism in the mandible or maxilla

Exclusion Criteria:

- patients who are known to be pregnant