A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee



Status:Archived
Conditions:Arthritis, Osteoarthritis (OA)
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:November 2007
End Date:November 2011

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Trial Summary
Trial Overview
Inclusion Criteria

A Long-Term, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Radiographic Study to Investigate the Safety and Efficacy of Orally Administered SD-6010 in Subjects With Symptomatic Osteoarthritis of the Knee


The objective of this 2-year study is to evaluate the safety, tolerability and disease
modifying efficacy of SD 6010, an inhibitor of inducible nitric oxide synthase (iNOS), in
overweight and obese subjects with knee osteoarthritis. The efficacy of SD-6010 will be
evaluated by radiography using joint space narrowing in the medial tibiofemoral compartment
of the study knee as the primary endpoint.



We found this trial at
34
sites
Pfizer Investigational Site
Arkansas City, Kansas 67005
782
mi
from 43215
Arkansas City, KS
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Massachusetts General Hospital
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
643
mi
from 43215
Boston, MA
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Pfizer Investigational Site
Akron, Ohio 44314
106
mi
from 43215
Akron, OH
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Pfizer Investigational Site
Alabaster, Alabama 35007
510
mi
from 43215
Alabaster, AL
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Pfizer Investigational Site
Anderson, South Carolina 29621
376
mi
from 43215
Anderson, SC
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Pfizer Investigational Site
Arvada, Colorado 80005
1168
mi
from 43215
Arvada, CO
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Pfizer Investigational Site
Asheville, North Carolina 28801
302
mi
from 43215
Asheville, NC
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Pfizer Investigational Site
Ashland, Kentucky 41101
105
mi
from 43215
Ashland, KY
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Pfizer Investigational Site
Atlanta, Georgia 30309
432
mi
from 43215
Atlanta, GA
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Pfizer Investigational Site
Auburn, Maine 04210
714
mi
from 43215
Auburn, ME
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Maine Research Associates
Auburn, Maine 04210
714
mi
from 43215
Auburn, ME
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Pfizer Investigational Site
Avon, Indiana 46123
179
mi
from 43215
Avon, IN
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Pfizer Investigational Site
Baltimore, Maryland 21234
346
mi
from 43215
Baltimore, MD
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Raleigh Regional Cancer Center
Beckley, West Virginia 25801
179
mi
from 43215
Beckley, WV
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Pfizer Investigational Site
Biloxi, Mississippi 39531
740
mi
from 43215
Biloxi, MS
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Pfizer Investigational Site
Bloomingdale, Illinois 60108
297
mi
from 43215
Bloomingdale, IL
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Pfizer Investigational Site
Bossier City, Louisiana 71111
784
mi
from 43215
Bossier City, LA
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Pfizer Investigational Site
Bridgeport, Connecticut 06606
522
mi
from 43215
Bridgeport, CT
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Pfizer Investigational Site
Bristol, Tennessee 37620
239
mi
from 43215
Bristol, TN
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Pfizer Investigational Site
Burke, Virginia 22015
317
mi
from 43215
Burke, VA
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Fletcher Allen Health Care
111 Colchester Ave
Burlington, Vermont 05401
(802) 847-0000
Fletcher Allen Health Care As Vermont’s University Medical Center, we at Fletcher Allen are committed...
590
mi
from 43215
Burlington, VT
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Pfizer Investigational Site
Cape Girardeau, Missouri 63703
397
mi
from 43215
Cape Girardeau, MO
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Pfizer Investigational Site
Cranston, Rhode Island 02920
617
mi
from 43215
Cranston, RI
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Darien Pediatric Associates
106 Noroton Ave
Darien, Connecticut 06820
(203) 655-9741
Darien Pediatric Associates Our office is pleased and privileged to care for your children and...
506
mi
from 43215
Darien, CT
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Pfizer Investigational Site
Fargo, North Dakota 58104
837
mi
from 43215
Fargo, ND
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Pfizer Investigational Site
Fayetteville, Arkansas 72703
659
mi
from 43215
Fayetteville, AR
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Pfizer Investigational Site
Honolulu, Hawaii 96814
4501
mi
from 43215
Honolulu, HI
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Pfizer Investigational Site
Houston, Texas 77030
995
mi
from 43215
Houston, TX
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Pfizer Investigational Site
Incline Village, Nevada 89451
1952
mi
from 43215
Incline Village, NV
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Pfizer Investigational Site
Los Angeles, California 90027
1982
mi
from 43215
Los Angeles, CA
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Pfizer Investigational Site
Madison, Wisconsin 53713
391
mi
from 43215
Madison, WI
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Strong Memorial Hospital (University of Rochester School of Medicine)
601 Elmwood Ave
Rochester, New York 14642
(585) 275-2100
Strong Memorial Hospital (University of Rochester School of Medicine) In addition to offering traditional and...
358
mi
from 43215
Rochester, NY
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Pfizer Investigational Site
Seattle, Washington 98166
2007
mi
from 43215
Seattle, WA
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Pfizer Investigational Site
West Jordan, Utah 84088
1519
mi
from 43215
West Jordan, UT
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