A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee



Status:Archived
Conditions:Arthritis, Osteoarthritis (OA)
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:November 2007
End Date:November 2011

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Trial Summary
Trial Overview
Inclusion Criteria

A Long-Term, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Radiographic Study to Investigate the Safety and Efficacy of Orally Administered SD-6010 in Subjects With Symptomatic Osteoarthritis of the Knee


The objective of this 2-year study is to evaluate the safety, tolerability and disease
modifying efficacy of SD 6010, an inhibitor of inducible nitric oxide synthase (iNOS), in
overweight and obese subjects with knee osteoarthritis. The efficacy of SD-6010 will be
evaluated by radiography using joint space narrowing in the medial tibiofemoral compartment
of the study knee as the primary endpoint.



We found this trial at
34
sites
Pfizer Investigational Site
Baltimore, Maryland 21234
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Massachusetts General Hospital
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
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Pfizer Investigational Site
Akron, Ohio 44314
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Alabaster, Alabama 35007
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Anderson, South Carolina 29621
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Arkansas City, Kansas 67005
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Arvada, Colorado 80005
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Pfizer Investigational Site
Asheville, North Carolina 28801
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Ashland, Kentucky 41101
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Pfizer Investigational Site
Atlanta, Georgia 30309
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Pfizer Investigational Site
Auburn, Maine 04210
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Maine Research Associates
Auburn, Maine 04210
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Pfizer Investigational Site
Avon, Indiana 46123
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Raleigh Regional Cancer Center
Beckley, West Virginia 25801
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Pfizer Investigational Site
Biloxi, Mississippi 39531
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Pfizer Investigational Site
Bloomingdale, Illinois 60108
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Pfizer Investigational Site
Bossier City, Louisiana 71111
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Pfizer Investigational Site
Bridgeport, Connecticut 06606
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Bristol, Tennessee 37620
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Pfizer Investigational Site
Burke, Virginia 22015
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Fletcher Allen Health Care
111 Colchester Ave
Burlington, Vermont 05401
(802) 847-0000
Fletcher Allen Health Care As Vermont’s University Medical Center, we at Fletcher Allen are committed...
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Burlington, VT
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Pfizer Investigational Site
Cape Girardeau, Missouri 63703
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Pfizer Investigational Site
Cranston, Rhode Island 02920
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Darien Pediatric Associates
106 Noroton Ave
Darien, Connecticut 06820
(203) 655-9741
Darien Pediatric Associates Our office is pleased and privileged to care for your children and...
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Darien, CT
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Pfizer Investigational Site
Fargo, North Dakota 58104
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Pfizer Investigational Site
Fayetteville, Arkansas 72703
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Pfizer Investigational Site
Honolulu, Hawaii 96814
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Honolulu, HI
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Pfizer Investigational Site
Houston, Texas 77030
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Pfizer Investigational Site
Incline Village, Nevada 89451
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Pfizer Investigational Site
Los Angeles, California 90027
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Pfizer Investigational Site
Madison, Wisconsin 53713
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Strong Memorial Hospital (University of Rochester School of Medicine)
601 Elmwood Ave
Rochester, New York 14642
(585) 275-2100
Strong Memorial Hospital (University of Rochester School of Medicine) In addition to offering traditional and...
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Pfizer Investigational Site
Seattle, Washington 98166
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Pfizer Investigational Site
West Jordan, Utah 84088
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