A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee



Status:Archived
Conditions:Arthritis, Osteoarthritis (OA)
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:November 2007
End Date:November 2011

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Trial Summary
Trial Overview
Inclusion Criteria

A Long-Term, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Radiographic Study to Investigate the Safety and Efficacy of Orally Administered SD-6010 in Subjects With Symptomatic Osteoarthritis of the Knee


The objective of this 2-year study is to evaluate the safety, tolerability and disease
modifying efficacy of SD 6010, an inhibitor of inducible nitric oxide synthase (iNOS), in
overweight and obese subjects with knee osteoarthritis. The efficacy of SD-6010 will be
evaluated by radiography using joint space narrowing in the medial tibiofemoral compartment
of the study knee as the primary endpoint.



We found this trial at
34
sites
Pfizer Investigational Site
Seattle, Washington 98166
12
mi
from 98109
Seattle, WA
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Massachusetts General Hospital
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
2485
mi
from 98109
Boston, MA
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Pfizer Investigational Site
Akron, Ohio 44314
2041
mi
from 98109
Akron, OH
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Pfizer Investigational Site
Alabaster, Alabama 35007
2091
mi
from 98109
Alabaster, AL
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Pfizer Investigational Site
Anderson, South Carolina 29621
2227
mi
from 98109
Anderson, SC
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Pfizer Investigational Site
Arkansas City, Kansas 67005
1474
mi
from 98109
Arkansas City, KS
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Pfizer Investigational Site
Arvada, Colorado 80005
1010
mi
from 98109
Arvada, CO
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Pfizer Investigational Site
Asheville, North Carolina 28801
2187
mi
from 98109
Asheville, NC
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Pfizer Investigational Site
Ashland, Kentucky 41101
2075
mi
from 98109
Ashland, KY
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Pfizer Investigational Site
Atlanta, Georgia 30309
2177
mi
from 98109
Atlanta, GA
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Pfizer Investigational Site
Auburn, Maine 04210
2471
mi
from 98109
Auburn, ME
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Maine Research Associates
Auburn, Maine 04210
2471
mi
from 98109
Auburn, ME
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Pfizer Investigational Site
Avon, Indiana 46123
1857
mi
from 98109
Avon, IN
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Pfizer Investigational Site
Baltimore, Maryland 21234
2328
mi
from 98109
Baltimore, MD
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Raleigh Regional Cancer Center
Beckley, West Virginia 25801
2167
mi
from 98109
Beckley, WV
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Pfizer Investigational Site
Biloxi, Mississippi 39531
2125
mi
from 98109
Biloxi, MS
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Pfizer Investigational Site
Bloomingdale, Illinois 60108
1710
mi
from 98109
Bloomingdale, IL
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Pfizer Investigational Site
Bossier City, Louisiana 71111
1820
mi
from 98109
Bossier City, LA
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Pfizer Investigational Site
Bridgeport, Connecticut 06606
2424
mi
from 98109
Bridgeport, CT
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Pfizer Investigational Site
Bristol, Tennessee 37620
2168
mi
from 98109
Bristol, TN
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Pfizer Investigational Site
Burke, Virginia 22015
2314
mi
from 98109
Burke, VA
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Fletcher Allen Health Care
111 Colchester Ave
Burlington, Vermont 05401
(802) 847-0000
Fletcher Allen Health Care As Vermont’s University Medical Center, we at Fletcher Allen are committed...
2325
mi
from 98109
Burlington, VT
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Pfizer Investigational Site
Cape Girardeau, Missouri 63703
1801
mi
from 98109
Cape Girardeau, MO
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Pfizer Investigational Site
Cranston, Rhode Island 02920
2486
mi
from 98109
Cranston, RI
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Darien Pediatric Associates
106 Noroton Ave
Darien, Connecticut 06820
(203) 655-9741
Darien Pediatric Associates Our office is pleased and privileged to care for your children and...
2414
mi
from 98109
Darien, CT
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Pfizer Investigational Site
Fargo, North Dakota 58104
1192
mi
from 98109
Fargo, ND
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Pfizer Investigational Site
Fayetteville, Arkansas 72703
1643
mi
from 98109
Fayetteville, AR
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Pfizer Investigational Site
Honolulu, Hawaii 96814
2679
mi
from 98109
Honolulu, HI
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Pfizer Investigational Site
Houston, Texas 77030
1892
mi
from 98109
Houston, TX
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Pfizer Investigational Site
Incline Village, Nevada 89451
591
mi
from 98109
Incline Village, NV
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Pfizer Investigational Site
Los Angeles, California 90027
979
mi
from 98109
Los Angeles, CA
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Pfizer Investigational Site
Madison, Wisconsin 53713
1618
mi
from 98109
Madison, WI
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Strong Memorial Hospital (University of Rochester School of Medicine)
601 Elmwood Ave
Rochester, New York 14642
(585) 275-2100
Strong Memorial Hospital (University of Rochester School of Medicine) In addition to offering traditional and...
2154
mi
from 98109
Rochester, NY
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Pfizer Investigational Site
West Jordan, Utah 84088
706
mi
from 98109
West Jordan, UT
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