Pazopanib in Previously Treated Patients With Metastatic Renal Cell Carcinoma
| Status: | Archived |
|---|---|
| Conditions: | Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | August 2008 |
| End Date: | November 2011 |
A Phase II Trial of Pazopanib in Patients With Metastatic Renal Cell Carcinoma Previously Treated With Sunitinib or Bevacizumab
This is a Phase II, non-randomized, open-label, single-arm study in patients with metastatic
renal cell carcinoma who have received one prior targeted therapy with either sunitinib or
bevacizumab. The planned enrollment for this study is 60 patients.
All eligible patients will receive 800 mg of pazopanib orally each day continuously.
Patients will be re-evaluated for treatment response after 8 weeks of daily oral pazopanib
therapy. Response to therapy will be assigned using RECIST criteria (Section 6.0)
Patients who have objective response or stable disease will continue treatment with
evaluations every 8 weeks, until the time of tumor progression or intolerable
treatment-related side effects.
We found this trial at
19
sites
166 Stoneridge Drive
Columbia, South Carolina 29210
Columbia, South Carolina 29210
803-461-3000
South Carolina Oncology Associates, PA South Carolina Oncology Associates (SCOA) is the only comprehensive cancer...
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Center for Cancer & Blood Disorders Widely recognized for its compassionate, expert care, the Center...
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Oncology Hematology Care Our more than 60 physicians and advanced practice providers throughout neighborhood offices...
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Tennessee Oncology, PLLC Since 1976 Tennessee Oncology has been providing quality cancer care. In 2013,...
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