Varenicline-Methamphetamine Interaction Study
| Status: | Archived |
|---|---|
| Conditions: | Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | August 2009 |
| End Date: | July 2011 |
A Human Laboratory Assessment of the Safety and Potential Efficacy of Varenicline In Methamphetamine-Dependent Volunteers Receiving Methamphetamine
The primary aim of the study is to determine the safety and tolerability of treatment with
Varenicline in methamphetamine-dependent volunteers. The investigators also seek to
determine the effects of treatment with Varenicline, as compared to placebo, on craving for
methamphetamine or cigarettes following exposure to methamphetamine and smoking cues,
respectively. The effects of treatment with Varenicline, as compared to placebo, on
subjective effects produced by administration of methamphetamine or placebo will be
attempted to be determined. Lastly, the investigators hope to determine the effects of
treatment with Varenicline, as compared to placebo, on reinforcing effects produced by
administration of methamphetamine or placebo.
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