Women Veterans' Substance Abuse Treatment

Substance use disorder (SUD) is problem among women military Veterans, especially younger
ones. The goal of this study was to examine the efficacy a gender-focused model of SUD
treatment (A Woman's Path to Recovery, WPR) compared to an evidence-based active comparator
that is not gender-specific (12-Step Facilitation, 12SF), in a sample of for women Veterans.
The investigators randomized 66 women Veterans, ages 18-65, who were diagnosed with current
SUD and used substances in the last 90 days. The treatment phase was 12 weekly individual
therapy sessions and all participants could also obtain treatment-as-usual (any other
treatments they chose to attend). Assessments were conducted at baseline, end of treatment
and 3-month follow up. Sample size was based on power analysis (an effect of .80 at a .05
level of significance). The primary outcome variable was substance use, with various
secondary outcomes also studied (e.g., psychosocial functioning, psychiatric symptoms, coping
skills, 12-step attendance). Urinalysis / breathalyzer (biological measures) were also
included to validate substance use self-report. The investigators hypothesized that
participants in the experimental condition (WPR) would have more positive outcomes on both
primary and secondary variables compared to those in the comparison condition (12SF). The
investigators also hypothesized that WPR patients would increase coping skills more and 12SF
would increase 12-step attendance more, relative to the other condition.

Inclusion Criteria:

- Female Veteran

- 18-65 years of age

- Meet DSM-IV criteria for current SUD with "current" defined as meeting SUD criteria
per the DSM-IV and having used a substance within the 90 days prior to intake (to be
able to accurately evaluate changes in their substance use from baseline)

- Plan to stay in the Boston area for the next 6 months

- Have a mailing address and live close enough to come to the hospital once weekly for
treatment and/or assessment

- Able to complete the Statement of Informed Consent

- Willing to participate in all assessments and breathalyzer/urine testing

- Willing to provide a release of information such that study staff can contact her
other providers as needed regarding any concerns during her participation

- Able to obtain medical clearance

- Willing to allow us to contact family and/or friends if participant loses contact with
us

- Literate

- Not pregnant or planning to become pregnant

Exclusion Criteria:

- Any acute medical condition that would interfere with the participant's ability to
participate in treatment, or would be of such severity as to affect the individual's
psychological functioning (e.g., cancer)

- Current bipolar I disorder, schizophrenia or other psychotic disorders or mental
retardation or organic mental disorder (determined by screening interview)

- Any clinical sign that the client is not sufficiently stable to participate in the
treatment, such as client's treatment provider indicating that participation in the
treatment would be contraindicated

- Dangerousness that would present a threat to other staff or other clients (e.g.,
history of recent assault)

- Client is mandated to treatment

- Psychopharmacologic treatment that is planned to change or likely to change
substantively over the 3-month active treatment phase (with "substantive" defined as
any addition of a new medication or major shift in dosage)