A Complicated Skin and Soft-Tissue Infection Patient Registry

A prospective, multi-center, observational study involving 1200 patients hospitalized for
the treatment of cSSTIs. The study will be conducted at approximately 50 hospitals in the
US. Patients who consent to participate in the registry will be enrolled in the registry
within 24 hours of initial IV antibiotic therapy for treatment of one or more cSSTI types.
Sites will treat patients according to their usual clinical practice. The objective of this
registry is to characterize cSSTIs with respect to patient characteristics and describe
patient outcomes.

N/A

Inclusion Criteria:

- Patients with a diagnosis of complicated skin and soft-tissue infection

- Patients who require IV antibiotic therapy as a primary treatment regimen

- Patients who are deemed to be cognitive and able to provide written informed consent
and follow-up information

Exclusion Criteria:

- Patients with a diagnosis at the index infection site of necrotizing soft tissue
infection, burn, gangrene, decubitus ulcer, animal or human bites, known or suspected
osteomyelitis, or mediastinitis

- Patients for whom amputation or a complete resection of the infection site is a
planned component of treatment

- Patients who are pregnant

- Patients simultaneously participating in any interventional clinical trial

- Patients with any other known or suspected condition that may jeopardize adherence to
registry protocol requirements

- Patients who are employees of the investigator or study hospital