MRI Screening for Patients With Myelodysplastic Syndrome (MDS), Who Have Received Multiple Red Blood Cell Transfusions
| Status: | Completed |
|---|---|
| Conditions: | Blood Cancer, Hematology |
| Therapuetic Areas: | Hematology, Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 10/27/2018 |
| Start Date: | July 31, 2008 |
| End Date: | March 29, 2013 |
T2* Cardiac MRI Screening of Highly Transfused Patients With Myelodysplastic Syndrome
A known risk of red blood cell transfusions is that it puts excess iron into the patient's
body. Researchers are continually seeking the most effective method of measuring iron
concentration. The purpose of this study is to determine how much iron has been deposited in
a patient's heart and liver as a result of having received red blood cell transfusions using
magnetic resonance imaging (MRI).
body. Researchers are continually seeking the most effective method of measuring iron
concentration. The purpose of this study is to determine how much iron has been deposited in
a patient's heart and liver as a result of having received red blood cell transfusions using
magnetic resonance imaging (MRI).
Inclusion Criteria:
- Male or Female patients will need documentation of diagnosis of Myelodysplastic
Syndrome by previous bone marrow exam
- Male or female patients with MDS who have received at least 50 units of Red Blood Cell
Transfusions.
- Serum ferritin > 1,000
- Written informed consent by the patient.
Exclusion Criteria:
- Contraindication to MRI, including cardiac pacemaker, brain aneurysm clip, implanted
neurostimulator, insulin pump, cochlear implant, metal slivers in the eyes,
intrauterine device or any other MRI incompatible metal implants or intractable
claustrophobia.
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Weill Medical College of Cornell University Founded in 1898, and affiliated with what is now...
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