Post-conditioning to Reduce Infarct Size
| Status: | Archived |
|---|---|
| Conditions: | Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | September 2008 |
| End Date: | May 2012 |
Modification of Reperfusion by "Post-Conditioning" Reduces Infarct Size in Acute Myocardial Infarction
When angioplasty (PTCA) and stenting of the blood vessels of the heart is the treatment for
a Heart Attack, there is damage to the heart muscle that is caused by the sudden opening of
the blood vessels. This is called "reperfusion injury". The cell death is due to
inflammation and the generation of free radicals.
The primary objective of this study is to determine if post-conditioning(four brief (30
second) PTCA balloon inflations) reduces damage to the heart muscle. This will be measured
by heart enzyme tests-CK measurements- and by cardiac MRI.
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Abbott Northwestern Hospital Our hospital has a long and proud history as a health care...
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