Studies on the Expression and Functions of RLIP76 in Blood Samples of Healthy Human Subjects
| Status: | Completed |
|---|---|
| Conditions: | Healthy Studies |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | September 2008 |
| End Date: | September 2011 |
| Contact: | Jyotsana Singhal |
| Email: | jsinghal@hsc.unt.edu |
| Phone: | 817-735-0459 |
RLIP76 (Ral binding protein1) is a 76 kDa splice variant protein encoded by the human gene
(RALBP1, 18p11.22). It is a multifunctional modular protein found ubiquitously from
Drosophila to humans, in cells ranging from red blood cells to endothelial cells of the
brain. Its expression more predominant in breast, heart, liver and less so in colon and
brain parenchyma.
(RALBP1, 18p11.22). It is a multifunctional modular protein found ubiquitously from
Drosophila to humans, in cells ranging from red blood cells to endothelial cells of the
brain. Its expression more predominant in breast, heart, liver and less so in colon and
brain parenchyma.
RLIP76 is shown to be over expressed in a variety of cancer cells. However, no study has yet
been done on its expression on normal cells. The studies proposed in this project will study
the expression of RLIP76 in blood cells of healthy human subjects in the population of North
Texas region.
been done on its expression on normal cells. The studies proposed in this project will study
the expression of RLIP76 in blood cells of healthy human subjects in the population of North
Texas region.
Inclusion Criteria:
- Healthy as defined by lack of serious health conditions or diseases
Exclusion Criteria:
- Children, pregnant women, prisoners, persons with any medical condition that
precludes phlebotomy and persons unwilling or unable to provide consent will be
excluded.
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