A Randomized Trial Of PF-00299804 Taken Orally Versus Erlotinib Taken Orally For Treatment Of Advanced Non-Small Cell Lung Cancer That Has Progressed After One Or Two Prior Chemotherapy Regimen
Status: | Completed |
---|---|
Conditions: | Lung Cancer, Cancer |
Therapuetic Areas: | Oncology |
Healthy: | No |
Age Range: | 18 - 99 |
Updated: | 4/21/2016 |
Start Date: | November 2008 |
End Date: | August 2014 |
A Randomized Phase 2 Trial Of Pf-00299804 Versus Erlotinib For The Treatment Of Advanced Non-small Cell Lung Cancer After Failure Of At Least One Prior Chemotherapy Regimen
This study will compare PF-00299804 given orally on continuous schedule to the approved
drug, erlotinib, in patients whose non-small cell lung cancer has progressed after
chemotherapy; patients will be randomized to receive one of these drugs, and followed for
efficacy and tolerance of each.
drug, erlotinib, in patients whose non-small cell lung cancer has progressed after
chemotherapy; patients will be randomized to receive one of these drugs, and followed for
efficacy and tolerance of each.
Inclusion Criteria:
- advanced measurable Non-Small Cell Lung Cancer (NSCLC);
- progressed after 1-2 prior chemotherapy;
- Eastern Cooperative Oncology Group (ECOG) 0-2;
- tissue available for future KRAS/ EGFR testing
Exclusion Criteria:
- prior Epidermal Growth Factor Receptor (EGFR) targeted therapy;
- active or untreated Central Nervous System (CNS) metastases;
We found this trial at
23
sites
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1365 Clifton Rd NE
Atlanta, Georgia 30322
Atlanta, Georgia 30322
(404) 778-1900

Winship Cancer Institute at Emory University Winship Cancer Institute of Emory University is Georgia
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John B. Amos Cancer Center The John B. Amos Cancer Center located in Columbus, Georgia,...
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The West Clinic, PC Hello and welcome to our office. Although it is our pleasure...
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