Pennsylvania Study Of Chronic Obstructive Pulmonary Exacerbations
| Status: | Completed |
|---|---|
| Conditions: | Chronic Obstructive Pulmonary Disease, Pulmonary |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 40 - 80 |
| Updated: | 6/30/2017 |
| Start Date: | June 2004 |
| End Date: | May 2008 |
Pennsylvania Study of Chronic Obstructive Pulmonary Exacerbations (PA-SCOPE)
The overall purpose of PA-SCOPE is to determine why black and rural residents of
Pennsylvania might be at higher risk for deadly, debilitating, and costly hospitalizations
for chronic obstructive pulmonary disease (COPD)— and then to show that repeat acute
exacerbations in high-risk patients can be reduced with one simple intervention. We believe
that 1) COPD patients who are black or who live in rural areas of Pennsylvania are at higher
risk of acute exacerbations requiring hospitalization and 2) this elevated risk can be
reduced with one simple intervention: access to a 1-800 Temple Call Center where patients
can get immediate customized advice on managing COPD exacerbations in their early stages. We
will test these beliefs in PA-SCOPE. The collaborators with Temple University Hospital on
the PA-SCOPE project are Lancaster General Hospital, Western Pennsylvania Hospital, and the
Philadelphia College of Osteopathic Medicine.
Pennsylvania might be at higher risk for deadly, debilitating, and costly hospitalizations
for chronic obstructive pulmonary disease (COPD)— and then to show that repeat acute
exacerbations in high-risk patients can be reduced with one simple intervention. We believe
that 1) COPD patients who are black or who live in rural areas of Pennsylvania are at higher
risk of acute exacerbations requiring hospitalization and 2) this elevated risk can be
reduced with one simple intervention: access to a 1-800 Temple Call Center where patients
can get immediate customized advice on managing COPD exacerbations in their early stages. We
will test these beliefs in PA-SCOPE. The collaborators with Temple University Hospital on
the PA-SCOPE project are Lancaster General Hospital, Western Pennsylvania Hospital, and the
Philadelphia College of Osteopathic Medicine.
- Overall objective: To determine why African American and rural residents of
Pennsylvania might be at higher risk for deadly, debilitating, and costly
hospitalizations for COPD—and to show that repeat acute exacerbations in high-risk
patients can be reduced with one simple intervention--access to a 1-800 Temple Call
Center phone number where patients can get immediate customized advice on managing COPD
exacerbations in their early stages.
- Phase 1: To compare and contrast the influence of race and geographic location in COPD
exacerbation in relation to severity, comorbidities, treatment patterns, infection
rate. To identify potential risk factors for COPD exacerbations leading to
hospitalization.
- Phase 2: To reduce hospitalizations and deaths due to COPD exacerbations and to improve
patient quality of life, lung function, and everyday activity levels
Pennsylvania might be at higher risk for deadly, debilitating, and costly
hospitalizations for COPD—and to show that repeat acute exacerbations in high-risk
patients can be reduced with one simple intervention--access to a 1-800 Temple Call
Center phone number where patients can get immediate customized advice on managing COPD
exacerbations in their early stages.
- Phase 1: To compare and contrast the influence of race and geographic location in COPD
exacerbation in relation to severity, comorbidities, treatment patterns, infection
rate. To identify potential risk factors for COPD exacerbations leading to
hospitalization.
- Phase 2: To reduce hospitalizations and deaths due to COPD exacerbations and to improve
patient quality of life, lung function, and everyday activity levels
Inclusion Criteria:
- Phase 1 & Gene Expression: --Current hospitalization for COPD exacerbation
- Phase 1 & 2: COPD & ONE of the following criteria:
1. History of hospitalization for COPD exacerbation, OR
2. Currently on supplemental oxygen, OR
3. History of evaluation for lung transplant or LVRS, OR
4. >/= 6 months post-LVRS
- Phase 1 or 2:
1. Current or former smoker, >/= 20 pack-yr. smoking history
2. FEV1
3. Life expectancy of > 6 months
Exclusion Criteria:
- < 20 pack-yr. smoking history
- Diagnosis of pulmonary fibrosis, bronchiectasis, mediastinal mass, or presence of a
pulmonary mass
- Asthma
- FEV1 > 70% or FEV1/FVC >70%
We found this trial at
3
sites
Lancaster General Hospital For more than a century, Lancaster General Hospital has been a leader...
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Western Pennsylvania Hospital Featuring 308 private patient beds, West Penn Hospital has served Bloomfield and...
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