Fatigue, Sleep Disorders and Endocrine Abnormalities in TBI Patients



Status:Completed
Conditions:Hospital, Neurology, Women's Studies
Therapuetic Areas:Neurology, Other, Reproductive
Healthy:No
Age Range:18 - 70
Updated:4/2/2016
Start Date:May 2003
End Date:December 2009
Contact:Anthony Lequerica, Ph.D.
Email:alequerica@kesslerfoundation.net
Phone:973-324-3551

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The Relationship Between Fatigue, Sleep Disorders and Endocrine Abnormalities Following Traumatic Brain Injury

This study will test if patients with moderate to severe traumatic brain injuries also have
endocrine abnormalities, examine any existing relationships among fatigue, depression and
endocrine abnormalities, and the relationship between endocrine abnormalities, quality of
life, and community integration.


Inclusion Criteria:

- Having moderate to severe TBI at least 3 months prior to enrollment. This can be
demonstrated by a history of loss of consciousness, amnesia or another neurologic
deficit after brain injury

- Be between the ages of 18 and 70 years

Exclusion Criteria:

- History of prior TBI, stroke, seizures, severe psychiatric disturbances (i.e., those
known to influence memory performance, such as schizophrenia, bipolar disorder), or
drug abuse will be excluded.

- Pregnant, nursing, or planning pregnancy during the study period.

- Dementia

- Other neurological conditions which are associated with aging and known to cause
fatigue (e.g. Parkinson's Disease)
We found this trial at
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West Orange, New Jersey 07052
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West Orange, NJ
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