Feasibility and Functionality of fPAM Imaging in Melanoma



Status:Completed
Conditions:Skin Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:11/30/2013
Start Date:January 2009
End Date:December 2014
Contact:Lynn A Cornelius, MD
Email:cornelil@wustl.edu
Phone:314-362-8187

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Determine the Feasibility and Functionality of fPAM Imaging for the in Vivo Characterization and Early Diagnosis of Melanoma


Melanoma is a cutaneous malignancy that has the potential for local (skin) and regional
(lymph node) recurrence. These recurrences may be difficult to detect in their earliest
stages. We are attempting to use novel form of skin imaging that uses ultrasound combined
with laser to identify these recurrences early, when they may be most amenable to treatment.
This imaging will detect melanoma pigment below the surface of the skin and in the draining
lymph nodes, as well as new blood vessel formation that occurs with these loco-regional
metastases.


recruiting healthy individuals with pigmented lesions and individuals with melanoma and
pigmented lesions

Inclusion Criteria:

- Adult patients (> 18 yrs of age) with recently diagnosed or a history of, Stage I -
III melanoma who are able to give informed consent.

Exclusion Criteria:

- Patients with melanomas < 1mm.

- Pregnant females.

- Children and young adults < 18 yrs of age and patients who are unable to give
informed consent.
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