Epidural Neostigmine for Labor Pain
| Status: | Completed |
|---|---|
| Conditions: | Women's Studies |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 9/13/2018 |
| Start Date: | October 2008 |
| End Date: | November 2013 |
Epidural Neostigmine Dose Response for the Treatment of Labor Pain
The purpose of this study is to see which dose of epidural neostigmine is the best additive
to use with the numbing medication used in an epidural during labor.
to use with the numbing medication used in an epidural during labor.
This study is examining the use of the non-narcotic medication, neostigmine, in combination
with the local anesthetic bupivacaine when compared with the commonly used narcotic fentanyl
in providing pain relief with the fewest side effects in labor analgesia.
with the local anesthetic bupivacaine when compared with the commonly used narcotic fentanyl
in providing pain relief with the fewest side effects in labor analgesia.
Inclusion Criteria:
- Healthy pregnancy
- Term pregnancy ( > 37 weeks)
- Primiparous or multiparous
- Induction or spontaneous labor greater or = 18 years of age
- Cervical exam on entry
Exclusion Criteria:
- Weight > 115 kg
- Non-English speaking
- IV analgesics within 60 minutes prior to epidural being administered
- Allergy to local anesthetics or neostigmine
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