Change in Brain Bioenergetics in Bipolar Disorder in Response to Photic Stimulation
| Status: | Archived |
|---|---|
| Conditions: | Healthy Studies, Schizophrenia, Psychiatric, Bipolar Disorder |
| Therapuetic Areas: | Psychiatry / Psychology, Other |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | February 2010 |
| End Date: | June 2010 |
A Magnetic Resonance Spectroscopy Study of Change in Brain Bioenergetics in Bipolar Disorder in Response to Photic Stimulation
This study aims to gather additional information to support the theory that bipolar disorder
is due to cellular (mitochondrial) dysfunction. To test this theory adults with bipolar
disorder who are not currently symptomatic will receive a one-time brain scan (magnetic
resonance spectroscopy [MRS] scan) with light stimulation. To test whether any MRS findings
are specific to bipolar disorder, healthy controls and adults with schizophrenia will also
be included in this study.
This study will include males and females between the ages of 18 and 55 years. Participants
will include adults with stable bipolar disorder or schizophrenia as well as healthy
controls. The study involves a one-time visit that includes a clinical evaluation,
laboratory tests, and a magnetic resonance scan that will last approximately 90 minutes.
The procedures can also be separated into two study visits, if necessary.
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