PET Imaging and Bariatric Surgery
| Status: | Completed |
|---|---|
| Conditions: | Obesity Weight Loss |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 18 - 60 |
| Updated: | 4/21/2016 |
| Start Date: | January 2007 |
| End Date: | June 2012 |
The purpose of this study is to look at certain areas of the brain that are related to
addictive behaviors, such as overeating. These areas are called 'dopamine type 2 receptors'
(DRD2) and other studies have shown that obese people have less of these. We propose that
low DRD2 availability seen in morbidly obese subjects will change with weight loss
associated with bariatric surgery.
addictive behaviors, such as overeating. These areas are called 'dopamine type 2 receptors'
(DRD2) and other studies have shown that obese people have less of these. We propose that
low DRD2 availability seen in morbidly obese subjects will change with weight loss
associated with bariatric surgery.
Inclusion Criteria:
- Ages 18-60 years
- BMI equal to or greater than 40, or equal to or greater than 35 if there are 2 or
more co-morbidities
- Weight less than 350 pounds
Exclusion Criteria:
- History of substance abuse,including but not limited to alcohol, cocaine, marijuana,
heroin, nicotine
- History of psychiatric disorders
- Use of any antidepressants or psychotropics in the past 12 months
- Diabetes Mellitis
- Positive pregnancy test
- Any condition felt by the PI or co-investigators to interfere with the individual's
ability to complete the study
- Subjects on medications for the last 3 months, such as sibutramine, which could
affect the quality of the study, as determined by the PI
- Inability to travel to Nashville, TN four times
We found this trial at
1
site
1211 Medical Center Dr
Nashville, Tennessee 37232
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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