Collection and Banking of Leukemia Cells for Vaccine Generation in Patients With Advanced Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML)
| Status: | Archived |
|---|---|
| Conditions: | Cancer, Blood Cancer, Hematology |
| Therapuetic Areas: | Hematology, Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | October 2008 |
| End Date: | December 2011 |
Collection and Banking of Leukemia Cells for Vaccine Generation and Research in Patients With Advanced MDS or AML
The goal of this research study is to determine if it is feasible to collect leukemia cells
from patients ahead of time (before they undergo further treatments) so that these cells
(after being radiated so they will no longer grow or divide) can be given back to them as a
cancer vaccine if/after the participant receives a bone marrow or blood stem cell transplant
in the future. The purpose of the research study will be to collect, freeze and store
leukemia calls from participants blood or bone marrow. This study is a companion study to a
vaccine study.
- Leukemia cells will be collected by one or more of the following methods: 1)Routine
blood draw 2)Bone marrow aspirate 3) Leukapheresis. The physician and study staff
will determine which of the methods above is best suited for each participant.
- After collection, the leukemia cells will be transported to the Cell Manipulation Core
Facility (CMCF) at the Dana-Farber Cancer Institute, where they will be frozen until
the time of vaccine administration.
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