Study Comparing Appearance and Function of Three Different Dental Implant Designs When Placed in Front Region of Upper Jaw

Inclusion Criteria:

- Provision of informed consent

- At least 18 years

- In need of one or more single implants replacing missing or non-restorable teeth in
the maxilla within region 14 to 24

The following should be considered at inclusion but can not be fulfilled until at Visit 2:

- Edentulous for at least 5 months at study site

- A buccal-lingual bone width at study site of at least 5.5 mm

- A mesial-distal bone level distance between adjacent teeth at study site of at least
5.5 mm

- A keratinized mid-buccal mucosal height of at least 2 mm at study site

- Teeth adjacent (mesial and distal) to study site must consist of two stable teeth on
natural roots without signs of periodontal bone loss (>1 mm) and/or significant soft
tissue loss

- Teeth adjacent (mesial and distal) to study site must demonstrate a stable occlusal
guidance that will allow non-functional disclusion in all eccentric positions

- An opposing dentition with teeth, implants or prosthesis

Exclusion Criteria:

- Insufficient interocclusal distance for implant placement and restoration at study
site

- Tooth adjacent (mesial and/or distal) to study site is ankylosed

- More than 2 mm vertical bone loss at study site as measured from the mid-buccal crest
of bone on the adjacent teeth

- Site development (bone tissue) performed at less than 5 months before Visit 2 at study
site

- Untreated rampant caries and/or uncontrolled periodontal disease

- Class II division 2 malocclusion (Edward Hartley Angle)

- Use of tobacco within last 6 months

- Uncontrolled diabetes (subjects history does not reveal the absence of control of
insulin-dependent/non-insulin dependent Diabetes Mellitus)

- Current alcohol or drug abuse

- Systemic or local disease or condition that would compromise post-operative healing
and/or osseointegration

- Use of any substance that will influence bone metabolism

- Need for systemic corticosteroids or any other medication that would influence
post-operative healing and/or osseointegration

- History of radiation in the head and neck region

- Known pregnancy, pregnancy tests will be performed as per local requirements.

- Unable or unwilling to return for follow-up visits for a period of 5 years

- Unlikely to be able to comply with study procedures according to Investigators
judgement

- Involvement in the planning and conduct of the study (applies to both Astra Tech staff
or staff at the study center)

- Previous enrollment or randomization of treatment in the present study.