Comparison Study of Daily Ultrafiltration and Twice-weekly Hemodialysis

In this study, the researchers want to find out how patients who have ultrafiltration
(removal of excess fluid) 6 times a week and twice-weekly dialysis (removal of excess fluid
and waste products) do in terms of their blood pressure and weight. The researchers believe
that maintaining patients at their estimated target weight throughout the week using daily
ultrafiltration will reduce their blood pressure to levels shown in other similar studies.
Such a reduction in blood pressure may reduce the incidence of cerebral vascular disease,
peripheral vascular disease, coronary artery disease, and congestive heart failure. The
researchers also believe that patients' quality of life will improve while they are
undergoing daily ultrafiltration.

Studies show that more frequent dialysis treatments result in fewer symptoms for patients.
The patients feel better and avoid the weight gains and symptoms that patients have on three
times a week dialysis. In addition, their blood lab results are better controlled, requiring
less medication.