6 Weeks Treatment of Locally Advanced Breast Cancer With BIBW 2992 (Afatinib) or Lapatinib or Trastuzumab



Status:Archived
Conditions:Breast Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:January 2009

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Randomised Phase II Study of Neoadjuvant BIBW 2992 Versus Herceptin Versus Lapatinib in Her2 Positive Breast Cancer Patients


An open-label, randomized three-arm Phase II trial to explore the efficacy of BIBW 2992 as a
single agent versus lapatinib versus trastuzumab in patients with HER2-positive
treatment-naïve Stage IIIa locally advanced breast cancer. Additional information will be
obtained on the safety profile and pharmacokinetics of BIBW 2992.



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