Evaluation of Patients With Thyroid Disorders



Status:Recruiting
Conditions:Cancer, Brain Cancer, Endocrine
Therapuetic Areas:Endocrinology, Oncology
Healthy:No
Age Range:Any
Updated:3/10/2019
Start Date:January 14, 1977
Contact:Craig S Cochran, R.N.
Email:craigc@bdg10.niddk.nih.gov
Phone:(301) 402-1880

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Evaluation of Patients With Thyroid Function Disorders

Participants in this study will be patients diagnosed with or suspected to have a thyroid
function disorder. These conditions may include: hypothyroidism, hyperthyroidism, thyroid
hormone resistance, Graves' Dermopathy, and thyroid-stimulating hormone (TSH) secreting
pituitary adenomas.

The main purpose of this study is to further understand the natural history, clinical
presentation, and genetics of thyroid function disorders. Many of the tests performed are in
the context of standard medical care that is offered to all patients with thyroid function
disorders. In addition, blood and tissue samples may be taken for research and genetic
studies.

Patients with thyroid function abnormalities (hyperthyroidism, hypothyroidism) are studied
and

treated in this protocol. A limited number of patients with a personal history of signs,
symptoms or laboratory studies consistent with thyroid dysfunction or a strong family history
of thyroid abnormalities are also enrolled. Patients undergo routine history and physical
examination, standard endocrine blood and urine tests, a standard TRH test, thyroid nuclear
medicine scan, thyroidal radioiodine (RAI) or technetium (99mTc) uptake measurements, as well
as X-ray, computed tomography (CT) or magnetic resonance imaging (MRI) studies or other
standard diagnostic procedures, as clinically indicated. Patients will be screened for entry
into other research studies.

- INCLUSION CRITERIA:

Patients of any age with known or suspected thyroid abnormalities may be included in this
study. These disorders can be broadly defined as hyper- or hypothyroid states and
laboratory abnormalities.
We found this trial at
1
site
9000 Rockville Pike
Bethesda, Maryland 20892
Phone: 800-411-1222
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Bethesda, MD
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