Ghrelin Regulation and Structure: Effect of Thiazolidinedione Therapy on Ghrelin
| Status: | Archived |
|---|---|
| Conditions: | Obesity Weight Loss, Endocrine |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | February 2009 |
| End Date: | May 2011 |
The purpose of this study is to learn more about how insulin resistance (inability to
process glucose correctly resulting in mildly elevated glucose levels) affects the hormone
ghrelin.
Insulin resistance suppresses fasting ghrelin levels and impairs postprandial ghrelin
suppression. Improved insulin sensitivity with a thiazolidinedione will raise ghrelin
levels, enhance meal-related suppression, but not change the ratio of total to active
ghrelin or result in an alteration of ghrelin structure.
We found this trial at
1
site
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
Portland, Oregon 97239
503 494-8311
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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