Hyperpolarized Noble Gas MR Imaging for Pulmonary Disorders
Status: | Archived |
---|---|
Conditions: | Asthma, Chronic Obstructive Pulmonary Disease, Healthy Studies, Pulmonary |
Therapuetic Areas: | Pulmonary / Respiratory Diseases, Other |
Healthy: | No |
Age Range: | Any |
Updated: | 7/1/2011 |
Start Date: | November 2008 |
End Date: | October 2017 |
The purpose of this study is to test the efficacy of Hyperpolarized Helium-3 gas in MR
imaging.
Current pulmonary imaging techniques are clinically regulated to machines that produce
radiation. MR which does not produce radiation was not possible due to the low concentration
of fluids in the open spaces of the lungs. With hyperpolarized noble gases we can now use
the safe techniques of MR imaging to view the airways of the lungs, thus limiting human
exposure to radiation. This technique has already been proven to be possible in human
subjects but there is insufficient data show its efficacy in a clinical setting. This study
is designed to image a variety of pulmonary disorders to better find possible clinical uses
for hyperpolarized gas MRI.
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