Mapping Mood in the Subthalamic Nucleus in Parkinson's Disease (PD)
| Status: | Completed |
|---|---|
| Conditions: | Anxiety, Depression, Parkinsons Disease |
| Therapuetic Areas: | Neurology, Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 40 - Any |
| Updated: | 5/5/2016 |
| Start Date: | December 2008 |
| End Date: | December 2015 |
Mapping Mood in the Subthalamic Nucleus in PD
The goal of this study is to determine the vulnerability of mood-related neurocircuitry in
Parkinson Disease (PD) using deep brain stimulation of the subthalamic nucleus (STN DBS).
Parkinson Disease (PD) using deep brain stimulation of the subthalamic nucleus (STN DBS).
Inclusion Criteria for STN-DBS subjects:
- Age 40 or older
- DBS STN Surgery in past 2 to 36 months
- Ability to tolerate turning off Stimulators
- Ability to read and comprehend questions
- English speaking
Exclusion Criteria for STN-DBS subjects:
- Other severe complications post surgery: stroke, seizure, major loss of
consciousness, other brain trauma/surgery, or head injuries(i.e. near drowning),
encephalitis, or hydrocephalus, blindness, deafness
- Clinically determined Dementia ( Most recent MMSE score of >24)
Inclusion Criteria for Control subject:
- Age 40 or older
- Ability to read and comprehend questions
- English speaking
Exclusion Criteria for Control subject:
- Other severe complications post surgery: stroke, seizure, major loss of
consciousness, other brain trauma/surgery, or head injuries(i.e. near drowning),
encephalitis, or hydrocephalus, blindness, deafness
- Clinically determined Dementia ( Most recent MMSE score of >24)
- Plans to have DBS STN surgery in the next 24 months
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