Sleep and Glucose Regulation in Youth With Type 1 Diabetes Mellitus
Status: | Archived |
---|---|
Conditions: | Insomnia Sleep Studies, Diabetes |
Therapuetic Areas: | Endocrinology, Psychiatry / Psychology |
Healthy: | No |
Age Range: | Any |
Updated: | 7/1/2011 |
Start Date: | February 2009 |
End Date: | March 2010 |
The purpose of this project is to look at how sleep affects glucose values in children with
Type 1 Diabetes Mellitus. It will also evaluate if glucose is affected by times of day due
to the body's own internal rhythm also known as the circadian rhythm.
Diabetes Mellitus (DM) is one of the most prevalent chronic pediatric diseases, affecting
2.80 cases per 1000 youth between the ages of 10 and 19. Since the crux of diabetes
management is glucose regulation, any further challenges such as stress and/or poor sleep
may make glucose regulation even more difficult. Mounting evidence supports the association
between inadequate sleep and obesity as well as metabolic syndrome. Despite emerging
findings supporting that total sleep time (TST) may contribute to the risk of obesity and/or
metabolic complications, less research has been focused on Type 1 Diabetes Mellitus (T1DM)
and on other sleep parameters.
Participants will have a Continuous Glucose Monitor (CGM) and actigraph placed which they
will wear for 5 days. At the end of the 5 days, they will return the glucose meter, CGM,
and actigraph to a clinic staff or research team member to download their data. They will
provide us with a glucose log that contains the glucose levels obtained from a fingerstick
capillary glucose meter. In this log, participants will also record their activities,
meals, and insulin administered. They will also provide us with a sleep diary. In
addition, participants will have the option for the child to undergo polysomnography (sleep
study) for one night in their home or two nights in the sleep lab.
We found this trial at
1
site
Steele Research Memorial Foundation, Angel Clinic for Children with Diabetes and Endocrine Disorders
Tucson, Arizona 85724
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