Myocardial Stress Perfusion Imaging With Dual Source CT



Status:Completed
Conditions:Peripheral Vascular Disease, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:40 - 90
Updated:12/19/2018
Start Date:April 2008
End Date:April 2010

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria
The investigators propose a novel technique using dual source multidetector computed
tomography (DSCT) where information on both coronary anatomy and myocardial perfusion is
obtained in a single scan. The investigators hypothesize that a coronary CTA protocol can be
devised to obtain resting myocardial perfusion, myocardial perfusion after stress, and
coronary anatomy. Hence, one diagnostic test will be able to detect the presence of coronary
plaque as well as assess the functional significance of a stenosis.


Inclusion Criteria:

- A prior adenosine or exercise stress SPECT exam with high likelihood of being referred
to the cardiac catheterization laboratory for invasive angiogram

- Age > 40 years old

- Able to comprehend and sign the consent form.

Exclusion Criteria:

- Acute coronary syndromes (unstable angina, non-ST elevation myocardial infarction, ST
elevation myocardial infarction)

- Unstable clinical conditions (i.e. hemodynamic instability, arrhythmias)

- Premenopausal women who have a positive pregnancy test.

- Serum Creatinine level ≥1.5 mg/dl as an indicator of renal insufficiency.

- Known allergy to iodinated contrast agents

- Atrial fibrillation

- Asthma

- Critical aortic stenosis

- Systolic blood pressure < 90 mmHg

- Advanced heart block
We found this trial at
1
site
Massachusetts General Hospital
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
Phone: 305-987-7412
?
mi
from
Boston, MA
Click here to add this to my saved trials