Family Research Study: Metabolism of Fats and Proteins in Specific Ethnic Groups
| Status: | Completed |
|---|---|
| Conditions: | Healthy Studies, Peripheral Vascular Disease, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Other |
| Healthy: | No |
| Age Range: | 6 - Any |
| Updated: | 2/8/2015 |
| Start Date: | February 2009 |
| End Date: | December 2015 |
| Contact: | Tina Tran |
| Phone: | 916-703-9127 |
Regulation of Lipoprotein(a) Metabolism in Humans With Reference to Ethnicity
The purpose of this study is to determine whether lipoprotein(a), also called Lp(a), is a
risk factor for cardiovascular (heart) disease. Lipoproteins are tiny particles that
circulate in the blood. They contain cholesterol, fat, and protein in varying amounts
depending on the body's need. Higher levels of lipoproteins in the blood can cause an
increased risk of heart disease.
The investigators believe that by studying the Lp(a) lipoprotein in Caucasians and African
Americans, the investigators can assess for genetic variation factors related to
cardiovascular (heart) disease. The investigators will be looking at 100 African-American
families and 100 Caucasian families to confirm whether a higher Lp(a) level is an indicator
of a higher risk for heart disease.
risk factor for cardiovascular (heart) disease. Lipoproteins are tiny particles that
circulate in the blood. They contain cholesterol, fat, and protein in varying amounts
depending on the body's need. Higher levels of lipoproteins in the blood can cause an
increased risk of heart disease.
The investigators believe that by studying the Lp(a) lipoprotein in Caucasians and African
Americans, the investigators can assess for genetic variation factors related to
cardiovascular (heart) disease. The investigators will be looking at 100 African-American
families and 100 Caucasian families to confirm whether a higher Lp(a) level is an indicator
of a higher risk for heart disease.
During the study visit the research staff will ask about the medical history, perform a
brief physical exam, and draw approximately 4 teaspoons of blood of each family member.
brief physical exam, and draw approximately 4 teaspoons of blood of each family member.
Inclusion Criteria:
- Of Caucasian or African descent
- Families must have 2 natural/biological parents and 2 natural/biological offspring
- 6 years old or older
Exclusion Criteria:
- Races other than African American or Caucasian
- Families without 2 natural/biological parents and 2 natural/biological offspring
- younger that 6 years old
We found this trial at
1
site
Mather, California 95655
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