NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer
| Status: | Recruiting |
|---|---|
| Conditions: | Colorectal Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 5/5/2014 |
| Start Date: | December 2008 |
| Contact: | Robert Medve, MD |
| Phone: | 415-482-5300 |
A Multicenter, Open-Label, Randomized, Phase 2 Study to Evaluate the Efficacy and Safety of NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naive, KRAS-Mutant, Metastatic Colorectal Cancer (mCRC)
This study will evaluate whether NKTR-102, an investigational drug has an anti-tumor effect
in patients with colorectal cancer. This study will also evaluate how the safety and
anti-tumor activity of NKTR-102 compares with irinotecan, a cancer drug that is approved for
use in the US for treatment of patients with certain types of colorectal cancer.
in patients with colorectal cancer. This study will also evaluate how the safety and
anti-tumor activity of NKTR-102 compares with irinotecan, a cancer drug that is approved for
use in the US for treatment of patients with certain types of colorectal cancer.
Inclusion Criteria:
- metastatic colorectal cancer
- tumor with k-ras mutation
Exclusion Criteria:
- More than 1 prior regimen for treatment of metastatic disease
We found this trial at
9
sites
Barbara Ann Karmanos Cancer Institute Karmanos is based in southeast Michigan, in midtown Detroit, and...
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1441 Eastlake Ave
Los Angeles, California 90033
Los Angeles, California 90033
(323) 865-3000
U.S.C./Norris Comprehensive Cancer Center The USC Norris Comprehensive Cancer Center, located in Los Angeles, is...
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