Biomechanical Assessment of Level Gait in Patient's Status Post Bladder Exstrophy

Status:	Completed
Conditions:	Urology
Therapuetic Areas:	Nephrology / Urology
Healthy:	No
Age Range:	4 - 65
Updated:	4/2/2016
Start Date:	April 2009
End Date:	June 2012
Contact:	John Makari, M.D.
Email:	jmakari@ccmckids.org
Phone:	860-545-9520

The purpose of this study is to determine whether patients who have undergone exstrophy
closure may be at risk for long-term orthopedic issues manifest by gait abnormalities. This
study is a descriptive analysis of the study cohort's gait patterns and pelvic structure.

Specific Aim 1: to determine whether patients with classic bladder exstrophy who underwent
closure demonstrate gait abnormalities.

Hypothesis 1: Patients undergoing closure of bladder exstrophy (with or without pelvic
osteotomy) demonstrate gait abnormalities compared with a reference population.

Hypothesis 2: Patients undergoing closure of bladder exstrophy (with or without pelvic
osteotomy) will have below normal functional survey scores.

Inclusion Criteria:

1. Subject was seen at CCMC for bladder exstrophy between January 2002 and December
2010.

2. Subject is four years of age or older at time of enrollment.

3. Subject has the ability to walk.

4. Subject has not had gait testing performed.

5. Subject provides Informed Consent and HIPAA Authorization.

Exclusion Criteria:

1. Subject was not seen at CCMC for bladder exstrophy between January 2002 and December
2010.

2. Subject under four years of age at time of enrollment.

3. Subject does not have the ability to walk.

4. Subject had prior gait testing performed.

5. Subject not willing to provide Informed Consent and HIPAA Authorization.

We found this trial at

sites

Connecticut Children's Medical Center

282 Washington St
Hartford, Connecticut 06106

(860) 545-9000