Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors
| Status: | Recruiting |
|---|---|
| Conditions: | Cancer, Brain Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/6/2019 |
| Start Date: | March 2009 |
| End Date: | September 2019 |
| Contact: | Robert Young, MD |
| Phone: | 212-639-8196 |
Using Advanced MR Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans: A Pilot Study, and to Examine Metabolite Changes in Gliomas and Other Solid Tumors
The purpose of this study is to assess the ability of these advanced MRI scans in predicting
areas within a malignant glioma (brain tumor) that are at a high risk of recurring. If these
advanced MRI scans are able to identify the cancerous part of the tumor, then radiation
therapy can be targeted to those sites and possibly improve patient survival.
areas within a malignant glioma (brain tumor) that are at a high risk of recurring. If these
advanced MRI scans are able to identify the cancerous part of the tumor, then radiation
therapy can be targeted to those sites and possibly improve patient survival.
Inclusion Criteria:
- Suspected or Histopathologically proven diagnosis of high grade or low glioma or tumor
is suspected to harbor an isocitrate dehydrogenase (IDH) mutation
- May undergo radiation therapy
- Patient and/or guardian is able to provide written informed consent prior to study
registration
- Age ≥ 18 years old
Exclusion Criteria:
- Extreme claustrophobia that precludes MRI scan
- Known allergic reaction to Gd-DTPA
- Any contraindication to gadolinium intravenous contrast as per standard Department of
Radiology contrast guidelines
- Any absolute contraindication to MRI (e.g., pacemaker, aneurysm clip, tissue
expander).
- Pregnant or nursing female
- Unable to cooperate for MRI and/or radiation therapy planning
We found this trial at
1
site
1275 York Ave
New York, New York 10021
New York, New York 10021
(212) 639-2000
Principal Investigator: Robert Young, MD
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
Click here to add this to my saved trials
