Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy

Extracorporeal shock wave lithotripsy is preferred for small stones less than 10 mm in size.
Percutaneous nephrolithotomy is the standard therapy used for large kidney stones greater
than 20 millimeters or stones in the lower kidney. For moderate sized kidney stone (10-20
mm),currently the options for treatment include both methods. However, no studies have
proven that one procedure is better than the other. So, we will compare both the procedures
for breaking the kidney stone. Our main outcome measures will be the stone-free status after
the procedure. Other outcome measures are assessment of morbidity associated with use of the
procedures i.e. any minor or major complications within 3 months of initial treatment.
Patient will be assessed for infection at post-operative office visits to include a basic
urinalysis only if they have systemic indicators of infection (fever, dysuria, frequency,
etc.). Pain will be monitored with the scale of 0-10 points. Also we will review of stone
density on Computerized Tomography (CT) scans and the effect this has on success of both
procedures. We hope with PCNL stone-free rates will be minimum with minimal morbidity and
ultimately improve patient care.

Inclusion Criteria:

- Patients of both sex with age greater than 18 years to 90 years

- Stone burden between 10 and 20 mm diagnosed by CT scan

- Patient must be agreeable to randomization between shock wave lithotripsy and
percutaneous stone removal

Exclusion Criteria:

- Patients with bleeding diathesis or taking anti-platelet or anti-coagulant medication

- Patients who are pregnant based on routine pre-operative pregnancy testing

- Patients with skin to stone size greater than 12 cm (measured routinely on CT scan)

- Patients with either Horseshoe kidney, transplant kidney or a solitary kidney

- Patients with ureteral calculi

- Patients with stone size of < 10 mm and > 20 mm

- Ureteropelvic junction obstruction