Study of STX-100 in Renal Transplant Patients With Interstitial Fibrosis and Tubular Atrophy (IF/TA)



Status:Archived
Conditions:Pulmonary
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:May 2009
End Date:December 2010

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Randomized Double-Blind, Placebo-Controlled, Single and Multiple Dose, Dose-Escalation Study of STX 100 in Renal Transplant Patients With Biopsy Proven Interstitial Fibrosis and Tubular Atrophy (IF/TA)


This Phase 2 study is a multi-center, randomized, double-blind, placebo-controlled, single
followed by multiple dose, dose escalation study designed to evaluate the safety,
tolerability, pharmacokinetics, immunogenicity, and impact of STX-100 on gene and protein
expression for αvβ6 related and TGF-β-inducible genes (including tubulointerstitial injury,
epithelial function, and IF/TA related genes) in renal transplant patients with biopsy.



We found this trial at
1
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Cambridge, Massachusetts 02141
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Cambridge, MA
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