Study of STX-100 in Renal Transplant Patients With Interstitial Fibrosis and Tubular Atrophy (IF/TA)
Status: | Archived |
---|---|
Conditions: | Pulmonary |
Therapuetic Areas: | Pulmonary / Respiratory Diseases |
Healthy: | No |
Age Range: | Any |
Updated: | 7/1/2011 |
Start Date: | May 2009 |
End Date: | December 2010 |
Randomized Double-Blind, Placebo-Controlled, Single and Multiple Dose, Dose-Escalation Study of STX 100 in Renal Transplant Patients With Biopsy Proven Interstitial Fibrosis and Tubular Atrophy (IF/TA)
This Phase 2 study is a multi-center, randomized, double-blind, placebo-controlled, single
followed by multiple dose, dose escalation study designed to evaluate the safety,
tolerability, pharmacokinetics, immunogenicity, and impact of STX-100 on gene and protein
expression for αvβ6 related and TGF-β-inducible genes (including tubulointerstitial injury,
epithelial function, and IF/TA related genes) in renal transplant patients with biopsy.
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