QT Variability Pre and Post Cardioversion



Status:Recruiting
Conditions:Atrial Fibrillation
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:21 - Any
Updated:3/30/2013
Start Date:January 2007
Contact:Raafia Muhammad, MD
Email:raafia.muhammad@vanderbilt.edu
Phone:504-352-0184

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QT Variability Pre & Post Cardioversion in Patient's With Atrial Fibrillation


The purpose of this study is to learn whether the chemicals in the blood and urine are
different when the heart is atrial fibrillation compared to normal sinus rhythm.


Atrial Fibrillation variably activates the renin-angiotensin-aldosterone system (RAAS),
stimulates the sympathetic nervous system, generates oxidant stress, produces natriuretic
peptides, and increases ventricular rate. These are interrelated responses and the extent
to which these or other pathophysiologic responses determine QT interval during and after
Atrial Fibrillation (AF) is unknown. In this study, the QT variability is related to those
potential markers in patients with AF undergoing elective DC-cardioversion.

Inclusion Criteria:

- At least 21 years of age

- Scheduled to undergo an elective DC-Cardioversion of atrial fibrillation or atrial
flutter at Vanderbilt University Medical Center

Exclusion Criteria:

- Undergoing emergent DC-Cardioversion of atrial fibrillation for hemodynamic
instability

- Undergoing DC-Cardioversion for post-cardiac surgery

- Dual chamber pacemakers
We found this trial at
1
site
1211 Medical Center Dr
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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Nashville, TN
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