A 16-Week, International, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Oral UT-15C Sustained Release Tablets in Subjects With Pulmonary Arterial Hypertension (FREEDOM-C2)



Status:Archived
Conditions:High Blood Pressure (Hypertension)
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:June 2009

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This study is an international, multi-center, randomized, double-blind, placebo-controlled
study in subjects with PAH who are currently receiving approved therapy for their PAH (i.e.,
endothelin receptor antagonist and/or phosphodiesterase-5 inhibitor). Study visits will
occur at 4 week intervals for 16 weeks with the key measure of efficacy being the 6-minute
walk test. Study procedures include routine blood tests, medical history, physical exams,
disease evaluation, and exercise tests.

Patients who complete all assessments for 16-weeks will also be eligible to enter an
open-label, extension phase study (FREEDOM - EXT).



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1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
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5801 South Ellis Avenue
Chicago, Illinois 60637
 773.702.1234
University of Chicago One of the world's premier academic and research institutions, the University of...
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234 Goodman Dr
Cincinnati, Ohio 45229
(513) 584-1000
University of Cincinnati Medical Center Opening in 1823 as the country
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5303 Harry Hines Boulevard
Dallas, Texas 75390
(214) 648-3111
UT Soutwestern Medical Center at Dallas UT Southwestern Medical Center is distinctive for its overall...
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Gainesville, Florida 32611
(352) 392-3261
University of Florida Gainesville UF has a long history of established programs in international education,...
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7000 Fannin St
Houston, Texas 77030
(713) 500-4472
University of Texas Health Science Center at Houston The University of Texas Health Science Center...
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101 Jessup Hall
Iowa City, Iowa 52242
(319) 335-3500
University of Iowa With just over 30,000 students, the University of Iowa is one of...
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1240 North Mission Road # L919
Los Angeles, California 90033
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3400 Spruce St
Philadelphia, Pennsylvania 19104
 (215) 662-4000
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22 Bramhall Street
Portland, Maine 04102
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3181 S.W. Sam Jackson Park Rd.
Portland, Oregon 97201
503 494-8311
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1 Brookings Drive
St. Louis, Missouri 63110
 (314) 935-5000
Washington University Washington University creates an environment to encourage and support an ethos of wide-ranging...
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2950 Cleveland Clinic Blvd.
Weston, Florida 33331
866.293.7866
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1 Akron General Ave
Akron, Ohio 44307
(330) 344-6000
Akron General Medical Center It
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Atlanta, Georgia 30322
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Aurora, Colorado 80045
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Boston, Massachusetts 02111
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101 Manning Dr
Chapel Hill, North Carolina 27599
(919) 966-4131
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850 Boylston Street
Chestnut Hill, Massachusetts 02467
1-800-BWH-9999
Brigham & Women's Hospital Women's Health Center At Brigham and Women
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10900 Euclid Ave
Cleveland, Ohio 44106
216-368-2000
Case Western Reserve Univ Continually ranked among America's best colleges, Case Western Reserve University has...
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281 W. Lane Ave
Columbus, Ohio 43210
(614) 292-6446
Ohio State University The Ohio State University’s main Columbus campus is one of America’s largest...
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2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
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Falls Church, Virginia 22042
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Kansas City, Kansas
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Los Angeles, California 90073
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Louisville, Kentucky 40202
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259 1st St
Mineola, New York 11501
(516) 663-0333
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5121 S Cottonwood St
Murray, Utah 84157
(801) 507-7000
Intermountain Medical Center Intermountain Medical Center is one of the most technologically advanced and patient-friendly...
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722 W 168th St
New York, New York 10032
(212) 305-2500
Columbia Presbyterian Med Ctr On January 1, 1998, The New York Hospital publicly announced its...
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201 Lyons Ave
Newark, New Jersey 07112
(973) 926-7000
Newark Beth Israel Medical Center Newark Beth Israel Medical Center, a regional care, teaching hospital...
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Phoenix, Arizona 85012
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Pittsburgh, Pennsylvania 15212
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200 Lothrop St
Pittsburgh, Pennsylvania 15213
University of Pittsburgh Medical Center UPMC is one of the leading nonprofit health systems in...
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Portland, Oregon 97210
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200 First Street SW
Rochester, Minnesota 55905
507-284-2511
Mayo Clinic Rochester Mayo Clinic is a nonprofit worldwide leader in medical care, research and...
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Sacramento, California 95817
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Torrance, California 90509
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