Task-oriented Training for Stroke: Impact on Function Mobility



Status:Completed
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:40 - 85
Updated:4/21/2016
Start Date:July 2011
End Date:January 2015

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Residual neurological deficits from stroke lead to gait inefficiencies, resulting in an
extremely high energy cost of movement and contributing to overall disability and lower
quality of life. Therefore, interventions targeting movement economy should be developed for
those in the chronic phase of stroke recovery. This study is designed to compare the effect
of two distinctly different exercise paradigms (a higher-intensity treadmill training
program and a lower-intensity group exercise program) on economy of movement during
over-ground walking and activities of daily living, as well as the extent to which gains in
muscular strength, muscular endurance, and balance predict changes in movement economy.


Inclusion Criteria:

- Stroke > 6 months prior with residual hemiparetic gait in women or men aged 40-85
years.

- Completion of all regular post-stroke physical therapy

- Adequate language and neurocognitive function to participate in testing and training
and to give adequate informed consent.

- Able to rise from a chair unaided.

- Able to walk 10 meters without human assistance.

Exclusion Criteria:

- Regular structured aerobic exercise (> 2x week).

- Alcohol consumption > 3 oz. liquor, or 3 x 4 oz glasses of wine, or 3 x 12 oz. beers
per day, by self-report.

- Clinical history of

- unstable angina,

- recent (< 3 months) myocardial infarction or congestive heart failure (NYHA
category II),

- hemodynamically significant valvular dysfunction,

- Peripheral Arterial Obstructive Disease with claudication,

- major orthopedic, chronic pain, or non-stroke neuromuscular disorders
restricting exercise,

- pulmonary or renal failure,

- poorly controlled hypertension (>190/110), measured on at least two separate
occasions

- recent hospitalization for severe disease or surgery

- severe or global receptive aphasia which confounds reliable testing and
training.

- Untreated major depression as documented by a Center for Epidemiological
Studies-Depression score of >16 and confirmed by clinical interview.

- Pregnancy.
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