Managerial Database II

The proposed study is a cross sectional study intended to be conducted at each of the
Adolescent Medicine Trials Units (AMTUs) newly participating in ATN III and to enroll all
participating patients followed at each site. This approach will allow for the examination
of the broad spectrum of youth participating in the ATN, including those newly entered into
care.

Psychosocial and risk-taking behavioral data will be collected using Audio Computer-Assisted
Self-Interview (ACASI) for English-speaking participants, or a paper-and-pencil
Spanish-language survey with identical measures to the ACASI for Spanish-speaking
participants; biomedical information will be collected through medical chart abstraction.

Inclusion Criteria:

- Laboratory evidence of HIV-1 infection documented by a positive result on any of the
following licensed tests at any time: Any HIV-1 antibody test confirmed by Western
blot, HIV-1 culture, HIV-1 DNA PCR, or plasma HIV-1 RNA PCR > 1,000 copies/ml;

- Knowledge of HIV positive diagnoses;

- Age 12 years through 24 years, inclusive, at the time of consent;

- Engaged in care at the AMTU or its affiliate and/or partnering clinic. Individuals
will be considered to be engaged in care if they have an AMTU (or its affiliate)
clinic visit during the enrollment period;

- Ability to understand written and/or verbal English or Spanish.

Exclusion Criteria:

- Presence of serious psychiatric symptoms (e.g., active hallucinations, thought
disorder) that would impair the individual's ability to complete the study measures;

- Visibly distraught (e.g., suicidal, homicidal, exhibiting violent behavior); or

- Intoxicated or under the influence of alcohol or other substances at the time of
consent/assent