Petrolatum's Effect on Initial Symptoms of Nonscalp Seborrheic Dermatitis and Preventing Exacerbation



Status:Completed
Conditions:Dermatology
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:18 - 75
Updated:4/2/2016
Start Date:March 2011
End Date:March 2012
Contact:Ryan D Stevenson, BS
Email:ryandavid26@yahoo.com
Phone:810-252-4951

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The goal of this research is to demonstrate the use of petroleum jelly in prevention of
nonscalp seborrheic dermatitis exacerbations at the first signs of a flare. In doing so, it
will decrease the chronic use of topical steroids. The use of petrolatum should have
favorable outcomes for patients, without the side-effects.

Nonscalp seborrheic dermatitis (NSSD) is typically a benign inflammatory process of the skin
that affects oil rich areas including in and between eyebrows, paranasal area, behind ears,
over the sternum, and groin. While these lesions typically come and go without proposing a
threat to the patient, they can be socially debilitating, and psychologically distressing.

The mainstay treatment for an exacerbation of NSSD is topical steroids. Topical steroids are
very effective and useful to patient's who are desperately seeking treatment. However, most
family practitioners are reluctant to prescribe or recommend topical steroids for chronic
conditions like NSSD due to the potential side-effects including permanent atrophy of the
skin.

NSSD has an unknown etiology. However, one of its biggest risk factors appears to be dry
skin due to its increase in incidence during colder seasons, and with use of
alcohol-containing topicals. Naturally occurring skin yeast (ie Malassezia) are also thought
to play a part.

Petrolatum is considered a skin protectant and has a strong ability to hold moisture in
skin. Along with restricting water from leaving skin, it also decreases most air from
contacting the skin. This may slow the growth and activity of skin yeast that are typically
considered facultative anaerobes.

A patient diagnosed with nonscalp seborrheic dermatitis will be consented into the study and
given instructions on the petroleum treatment. This includes wetting the affected area,
blotting dry, and then applying petrolatum to the area before bedtime. This regimen is to be
followed every other night until symptoms diminish. The patient will come back to the office
for follow-up at one week, two weeks, and four weeks after treatment begins to see the
outcome. Pictures will be taken at each encounter and used to measure progress through one
mm graphs. Patients will not be identifiable in these pictures, and they will be labeled
with the patient's given ID number.

Inclusion Criteria:

- Age 18-75 years old who are patients of the Genesys East Flint Clinic and have been
diagnosed with recurrent NSSD

- Patients are to use the petrolatum treatment strictly for the initial symptoms of
NSSD: Excessive flaking, and erythematous macules or papules

- Patients who are able to attend the follow-up appointments for assessment

- Patients are to have the doctor's confidence that that patient will correctly
implement the treatment plan

Exclusion Criteria:

- Patients not in the 18-75 years of age range.

- Patients who are receiving treatment for their seborrheic dermatitis (Scalp or
nonscalp) elsewhere.

- Patients who have not demonstrated recurrent NSSD.

- Patients who are unable to commit to a follow-up appointments for assessment.

- Patients who do not have the physician's confidence in implementing the studies
treatment plan effectively.

- Patient's who are unable/unwilling to have petrolatum on affected area for at least a
6 hour length of time.
We found this trial at
1
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Burton, Michigan 48509
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Burton, MI
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