Genetics Study of Wet Age-Related Macular Degeneration (AMD) Non-Responders to Vascular Endothelial Growth Factor (VEGF) Therapy
Status: | Active, not recruiting |
---|---|
Conditions: | Ocular |
Therapuetic Areas: | Ophthalmology |
Healthy: | No |
Age Range: | Any |
Updated: | 10/14/2018 |
Start Date: | April 2011 |
End Date: | June 2019 |
Genotypic Evaluation of Chronic Exudative Macular Degeneration Despite Monthly Anti-Vascular Endothelial Growth Factor (VEGF) Therapy
To obtain a genotypic analysis of patients with chronic exudative age-related macular
degeneration noted to have subretinal or intraretinal edema despite continuous monthly
Anti-VEGF therapy.
degeneration noted to have subretinal or intraretinal edema despite continuous monthly
Anti-VEGF therapy.
Inclusion Criteria:
- Ability to provide written informed consent for participation in this study
- Subjects diagnoses of neovascular AMD who are on a monthly anti-VEGF regimen (have had
>10 or more ranibizumab and/or bevacizumab injections within the last year) and who
still have intra-retinal or subretinal fluid as confirmed by the Investigator
Exclusion Criteria:
- Subjects with a Pigment Epithelial Detachment Exclusively
- Subjects with Serous Pigment Epithelial Detachments
- Subjects with history of the following:
idiopathic polypoidal choroidal vasculopathy
- pathologic degenerative myopia
- central serous chorioretinopathy
- familial drusen
- adult onset foveal pattern dystrophy
We found this trial at
1
site
Click here to add this to my saved trials
![](https://www.clinicaltrialsgps.com/wp-content/themes/GPS/media//img/tooltip-arrow.png)