A One-Year Study To Evaluate The Efficacy And Safety Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque Psoriasis



Status:Completed
Conditions:Psoriasis
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:18 - Any
Updated:10/14/2017
Start Date:March 2011
End Date:April 2013

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Trial Summary
Trial Overview
Inclusion Criteria

A Phase 3, Multi-Site, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Of The Efficacy And Safety Of 2 Oral Doses Of CP-690,550 In Subjects With Moderate To Severe Chronic Plaque Psoriasis

The main objective of this study is to compare the effects of CP-690,550 with the effects of
placebo in patients being treated for moderate to severe chronic plaque psoriasis. This
one-year study will also evaluate the safety and tolerability of CP-690,550 versus placebo.


Inclusion Criteria:

- 18 years or older with diagnosis for at least 12 months of moderate to severe plaque
psoriasis covering at least 10% of body surface area

- A Psoriasis Area and Severity Index (PASI) score of 12 or greater

- Are considered to be candidates for systemic or light therapy

- Have no evidence of active or latent tuberculosis

Exclusion Criteria:

- Non-plaque or drug-induced forms of psoriasis

- Cannot discontinue current oral, injectible or topical therapy for psoriasis or cannot
discontinue phototherapy (PUVA or UVB)

- Any uncontrolled significant medical condition
We found this trial at
45
sites
Dartmouth-Hitchcock Medical Center, Section of Dermatology
Lebanon, New Hampshire 03756
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Comprehensive Clinical Research
175 Cross Keys Rd.
Berlin, New Jersey 08009
856-753-7335
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Berlin, NJ
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University of Alabama at Birmingham
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
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Birmingham, AL
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Brigham and Women's Hosp
75 Francis street
Boston, Massachusetts 02115
(617) 732-5500
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
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Boston, MA
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University of North Carolina at Chapel Hill
Chapel Hill, North Carolina 27599
(919) 962-2211
University of North Carolina at Chapel Hill Carolina’s vibrant people and programs attest to the...
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Chapel Hill, NC
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Oregon Health and Science University
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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Portland, OR
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Progressive Clinical Research
4499 Medical Drive
San Antonio, Texas 78229
210-614-5557
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San Antonio, TX
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Sherman Immediate Care Center (Imaging Only)
600 South Randall Road
Algonquin, Illinois 60102
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Algonquin, IL
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Arlington Research Center
Arlington, Texas 76011
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Arlington, TX
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Austin Dermatology Associates
Austin, Texas 78705
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Austin, TX
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Bakersfield Dermatology and Skin Cancer Medical Group
Bakersfield, California 99309
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Bakersfield, CA
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Kirk Barber Research
Calgary, Alberta
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Calgary,
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University of North Carolina at Chapel Hill Hospital
Chapel Hill, North Carolina 27599
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Chapel Hill, NC
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Radiant Research, Inc
Columbus, Ohio 43212
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Columbus, OH
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Dermatology Treatment & Research Center, PA
Dallas, Texas 75230
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Dallas, TX
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InSight Diagnostic Center
Dallas, Texas 75243
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Dallas, TX
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Hudson Dermatology
Evansville, Indiana 47714
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Evansville, IN
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Hamzavi Dermatology
Fort Gratiot, Michigan 48059
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Fort Gratiot, MI
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Bettencourt Skin Center
Henderson, Nevada 89014
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Henderson, NV
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Penn State Milton S. Hershey Medical Center
500 University Dr
Hershey, Pennsylvania 17033
(717) 531-6955
Penn State Milton S. Hershey Medical Center Penn State Milton S. Hershey Medical Center, Penn...
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Hershey, PA
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Burke Pharmaceutical Research
Hot Springs, Arkansas 71913
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Hot Springs, AR
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Center for Clinical Studies
Houston, Texas 77030
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Houston, TX
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Suzanne Bruce & Associates, PA
Houston, Texas 77056
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Houston, TX
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North Florida Dermatology Associates, PA
Jacksonville, Florida 32204
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Jacksonville, FL
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The University of California, San Diego
9500 Gilman Dr
La Jolla, California 92093
(858) 534-2230
The University of California, San Diego UC San Diego is an academic powerhouse and economic...
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La Jolla, CA
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Dermatology Research Associates
Los Angeles, California 90045
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Los Angeles, CA
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Expresscare Medical (X-Rays only)
8930 South Sepulveda Boulevard
Los Angeles, California 90045
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Los Angeles, CA
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Dermatologic Surgery Specialists, Inc.
Macon, Georgia 31217
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Macon, GA
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University of Minnesota-Department of Dermatology
Minneapolis, Minnesota 55455
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Minneapolis, MN
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Rockefeller University
1230 York Ave
New York, New York 10065
(212) 327-8000
Rockefeller University The Rockefeller University is a world-renowned center for research and graduate education in...
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Virginia Clinical Research, Inc.
Norfolk, Virginia 23507
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Norfolk, VA
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Oregon Dermatology & Research Center
Portland, Oregon 97210
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Portland, OR
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Health Concepts
Rapid City, South Dakota 57702
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Rapid City, SD
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Saint Louis University - Department of Dermatology
Saint Louis, Missouri 63104
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Saint Louis, MO
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Office of Mark S. Lee, MD
San Antonio, Texas 78229
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San Antonio, TX
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Medderm Associates
San Diego, California 92103
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San Diego, CA
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University of California, San Diego
San Diego, California 92093
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San Diego, CA
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Schaumburg Dermatology
Schaumburg, Illinois 60173
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Schaumburg, IL
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NorthShore University HealthSystem - Division of Dermatology
Skokie, Illinois 60077
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Skokie, IL
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Central Dermatology
St. Louis, Missouri 63117
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St. Louis, MO
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Healthcare Partners Medical Group
Torrance, California 90503
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Torrance, CA
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Somerset Skin Centre - Dermcenter
Troy, Michigan 48084
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Troy, MI
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Center for Clinical Studies
Webster, Texas 77598
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Webster, TX
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Dundee Dermatology
West Dundee, Illinois 60118
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West Dundee, IL
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Wake Forest University Health Sciences
1 Medical Center Blvd
Winston-Salem, North Carolina 27157
336-716-2011
Wake Forest University Health Sciences Welcome to Wake Forest Baptist Medical Center, a fully integrated...
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